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Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity.
Lamers CH, Sleijfer S, van Steenbergen S, van Elzakker P, van Krimpen B, Groot C, Vulto A, den Bakker M, Oosterwijk E, Debets R, Gratama JW. Lamers CH, et al. Among authors: van elzakker p. Mol Ther. 2013 Apr;21(4):904-12. doi: 10.1038/mt.2013.17. Epub 2013 Feb 19. Mol Ther. 2013. PMID: 23423337 Free PMC article. Clinical Trial.
Process validation and clinical evaluation of a protocol to generate gene-modified T lymphocytes for imunogene therapy for metastatic renal cell carcinoma: GMP-controlled transduction and expansion of patient's T lymphocytes using a carboxy anhydrase IX-specific scFv transgene.
Lamers CH, van Elzakker P, Langeveld SC, Sleijfer S, Gratama JW. Lamers CH, et al. Among authors: van elzakker p. Cytotherapy. 2006;8(6):542-53. doi: 10.1080/14653240601056396. Cytotherapy. 2006. PMID: 17148030