Hardern I - Search Results

1

Development of a high-throughput fluorescence polarization DNA cleavage assay for the identification of FEN1 inhibitors.

McWhirter C, Tonge M, Plant H, Hardern I, Nissink W, Durant ST. McWhirter C, et al. Among authors: hardern i. J Biomol Screen. 2013 Jun;18(5):567-75. doi: 10.1177/1087057113476551. Epub 2013 Feb 20. J Biomol Screen. 2013. PMID: 23427045

2

A High-Throughput Screening Triage Workflow to Authenticate a Novel Series of PFKFB3 Inhibitors.

St-Gallay SA, Bennett N, Critchlow SE, Curtis N, Davies G, Debreczeni J, Evans N, Hardern I, Holdgate G, Jones NP, Leach L, Maman S, McLoughlin S, Preston M, Rigoreau L, Thomas A, Turnbull AP, Walker G, Walsh J, Ward RA, Wheatley E, Winter-Holt J. St-Gallay SA, et al. Among authors: hardern i. SLAS Discov. 2018 Jan;23(1):11-22. doi: 10.1177/2472555217732289. Epub 2017 Sep 25. SLAS Discov. 2018. PMID: 28945981 Free article.

3

A high-throughput screening-compatible homogeneous time-resolved fluorescence assay measuring the glycohydrolase activity of human poly(ADP-ribose) glycohydrolase.

Stowell AI, James DI, Waddell ID, Bennett N, Truman C, Hardern IM, Ogilvie DJ. Stowell AI, et al. Among authors: hardern im. Anal Biochem. 2016 Jun 15;503:58-64. doi: 10.1016/j.ab.2016.03.016. Epub 2016 Mar 29. Anal Biochem. 2016. PMID: 27036617

4

Enzymatic characterisation of USP7 deubiquitinating activity and inhibition.

Wrigley JD, Eckersley K, Hardern IM, Millard L, Walters M, Peters SW, Mott R, Nowak T, Ward RA, Simpson PB, Hudson K. Wrigley JD, et al. Among authors: hardern im. Cell Biochem Biophys. 2011 Jun;60(1-2):99-111. doi: 10.1007/s12013-011-9186-4. Cell Biochem Biophys. 2011. PMID: 21468692

5

Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening.

Bürli RW, Wei H, Ernst G, Mariga A, Hardern IM, Herlihy K, Cross AJ, Wesolowski SS, Chen H, McKay RDG, Weinberger DR, Brandon NJ, Barrow JC. Bürli RW, et al. Among authors: hardern im. Bioorg Med Chem Lett. 2018 Oct 15;28(19):3231-3235. doi: 10.1016/j.bmcl.2018.08.012. Epub 2018 Aug 14. Bioorg Med Chem Lett. 2018. PMID: 30170942

6

Utility of lab-on-a-chip technology for high-throughput nucleic acid and protein analysis.

Hawtin P, Hardern I, Wittig R, Mollenhauer J, Poustka A, Salowsky R, Wulff T, Rizzo C, Wilson B. Hawtin P, et al. Among authors: hardern i. Electrophoresis. 2005 Oct;26(19):3674-81. doi: 10.1002/elps.200500166. Electrophoresis. 2005. PMID: 16136523

7

Improvements to the throughput of recombinant protein expression in the baculovirus/insect cell system.

McCall EJ, Danielsson A, Hardern IM, Dartsch C, Hicks R, Wahlberg JM, Abbott WM. McCall EJ, et al. Among authors: hardern im. Protein Expr Purif. 2005 Jul;42(1):29-36. doi: 10.1016/j.pep.2005.03.021. Epub 2005 Apr 11. Protein Expr Purif. 2005. PMID: 15939290

8

Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is markedly dependent on the activation state of the enzyme.

Freeman S, Bartlett JB, Convey G, Hardern I, Teague JL, Loxham SJ, Allen JM, Poucher SM, Charles AD. Freeman S, et al. Among authors: hardern i. Br J Pharmacol. 2006 Nov;149(6):775-85. doi: 10.1038/sj.bjp.0706925. Epub 2006 Oct 3. Br J Pharmacol. 2006. PMID: 17016495 Free PMC article.

9

Engineered human carboxypeptidase B enzymes that hydrolyse hippuryl-L-glutamic acid: reversed-polarity mutants.

Edge M, Forder C, Hennam J, Lee I, Tonge D, Hardern I, Fitton J, Eckersley K, East S, Shufflebotham A, Blakey D, Slater A. Edge M, et al. Among authors: hardern i. Protein Eng. 1998 Dec;11(12):1229-34. doi: 10.1093/protein/11.12.1229. Protein Eng. 1998. PMID: 9930672

10

An analysis of two refolding routes for a C-terminally truncated human collagenase-3 expressed in Escherichia coli.

Hardern IM, Knauper V, Ernill RJ, Taylor IW, Cooper KL, Abbott WM. Hardern IM, et al. Protein Expr Purif. 2000 Jul;19(2):246-52. doi: 10.1006/prep.2000.1244. Protein Expr Purif. 2000. PMID: 10873537

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

11 results

Search Page

Filters