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A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients.
Higgs BW, Zhu W, Morehouse C, White WI, Brohawn P, Guo X, Rebelatto M, Le C, Amato A, Fiorentino D, Greenberg SA, Drappa J, Richman L, Greth W, Jallal B, Yao Y. Higgs BW, et al. Among authors: fiorentino d. Ann Rheum Dis. 2014 Jan;73(1):256-62. doi: 10.1136/annrheumdis-2012-202794. Epub 2013 Feb 23. Ann Rheum Dis. 2014. PMID: 23434567 Free PMC article. Clinical Trial.
Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway.
Higgs BW, Liu Z, White B, Zhu W, White WI, Morehouse C, Brohawn P, Kiener PA, Richman L, Fiorentino D, Greenberg SA, Jallal B, Yao Y. Higgs BW, et al. Among authors: fiorentino d. Ann Rheum Dis. 2011 Nov;70(11):2029-36. doi: 10.1136/ard.2011.150326. Epub 2011 Jul 28. Ann Rheum Dis. 2011. PMID: 21803750 Clinical Trial.
Genomic signatures characterize leukocyte infiltration in myositis muscles.
Zhu W, Streicher K, Shen N, Higgs BW, Morehouse C, Greenlees L, Amato AA, Ranade K, Richman L, Fiorentino D, Jallal B, Greenberg SA, Yao Y. Zhu W, et al. Among authors: fiorentino d. BMC Med Genomics. 2012 Nov 21;5:53. doi: 10.1186/1755-8794-5-53. BMC Med Genomics. 2012. PMID: 23171592 Free PMC article.
The plasma cell signature in autoimmune disease.
Streicher K, Morehouse CA, Groves CJ, Rajan B, Pilataxi F, Lehmann KP, Brohawn PZ, Higgs BW, McKeever K, Greenberg SA, Fiorentino D, Richman LK, Jallal B, Herbst R, Yao Y, Ranade K. Streicher K, et al. Among authors: fiorentino d. Arthritis Rheumatol. 2014 Jan;66(1):173-84. doi: 10.1002/art.38194. Arthritis Rheumatol. 2014. PMID: 24431284
2016 American College of Rheumatology/European League Against Rheumatism Criteria for Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis: An International Myositis Assessment and Clinical Studies Group/Paediatric Rheumatology International Trials Organisation Collaborative Initiative.
Aggarwal R, Rider LG, Ruperto N, Bayat N, Erman B, Feldman BM, Oddis CV, Amato AA, Chinoy H, Cooper RG, Dastmalchi M, Fiorentino D, Isenberg D, Katz JD, Mammen A, de Visser M, Ytterberg SR, Lundberg IE, Chung L, Danko K, García-De la Torre I, Song YW, Villa L, Rinaldi M, Rockette H, Lachenbruch PA, Miller FW, Vencovsky J; International Myositis Assessment and Clinical Studies Group and the Paediatric Rheumatology International Trials Organisation. Aggarwal R, et al. Among authors: fiorentino d. Arthritis Rheumatol. 2017 May;69(5):898-910. doi: 10.1002/art.40064. Epub 2017 Apr 6. Arthritis Rheumatol. 2017. PMID: 28382787 Free PMC article.
Capillary regeneration in scleroderma: stem cell therapy reverses phenotype?
Fleming JN, Nash RA, McLeod DO, Fiorentino DF, Shulman HM, Connolly MK, Molitor JA, Henstorf G, Lafyatis R, Pritchard DK, Adams LD, Furst DE, Schwartz SM. Fleming JN, et al. Among authors: fiorentino df. PLoS One. 2008 Jan 16;3(1):e1452. doi: 10.1371/journal.pone.0001452. PLoS One. 2008. PMID: 18197262 Free PMC article.
Editorial myositis and myopathies.
Fiorentino D, Casciola-Rosen L. Fiorentino D, et al. Curr Opin Rheumatol. 2024 Nov 1;36(6):427-429. doi: 10.1097/BOR.0000000000001056. Epub 2024 Oct 3. Curr Opin Rheumatol. 2024. PMID: 39584404 No abstract available.
255 results