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Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine.
de Wit N, Derrien M, Bosch-Vermeulen H, Oosterink E, Keshtkar S, Duval C, de Vogel-van den Bosch J, Kleerebezem M, Müller M, van der Meer R. de Wit N, et al. Among authors: van der meer r. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1;303(5):G589-99. doi: 10.1152/ajpgi.00488.2011. Epub 2012 Jun 14. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22700822 Free article.
A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine.
de Vogel-van den Bosch HM, de Wit NJ, Hooiveld GJ, Vermeulen H, van der Veen JN, Houten SM, Kuipers F, Müller M, van der Meer R. de Vogel-van den Bosch HM, et al. Among authors: van der veen jn, van der meer r. Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1171-80. doi: 10.1152/ajpgi.00360.2007. Epub 2008 Mar 20. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18356535 Free article.
Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages.
Lichtenstein L, Mattijssen F, de Wit NJ, Georgiadi A, Hooiveld GJ, van der Meer R, He Y, Qi L, Köster A, Tamsma JT, Tan NS, Müller M, Kersten S. Lichtenstein L, et al. Among authors: van der meer r. Cell Metab. 2010 Dec 1;12(6):580-92. doi: 10.1016/j.cmet.2010.11.002. Cell Metab. 2010. PMID: 21109191 Free PMC article.
Oit1/Fam3D, a gut-secreted protein displaying nutritional status-dependent regulation.
de Wit NJ, IJssennagger N, Oosterink E, Keshtkar S, Hooiveld GJ, Mensink RP, Hammer S, Smit JW, Müller M, van der Meer R. de Wit NJ, et al. Among authors: van der meer r. J Nutr Biochem. 2012 Nov;23(11):1425-33. doi: 10.1016/j.jnutbio.2011.09.003. Epub 2012 Jan 4. J Nutr Biochem. 2012. PMID: 22226334 Clinical Trial.
348 results