Harris JM - Search Results

1

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment.

Dong Y, Stephens C, Walpole C, Swedberg JE, Boyle GM, Parsons PG, McGuckin MA, Harris JM, Clements JA. Dong Y, et al. Among authors: harris jm. PLoS One. 2013;8(2):e57056. doi: 10.1371/journal.pone.0057056. Epub 2013 Feb 25. PLoS One. 2013. PMID: 23451143 Free PMC article.

2

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

Swedberg JE, Nigon LV, Reid JC, de Veer SJ, Walpole CM, Stephens CR, Walsh TP, Takayama TK, Hooper JD, Clements JA, Buckle AM, Harris JM. Swedberg JE, et al. Among authors: harris jm. Chem Biol. 2009 Jun 26;16(6):633-43. doi: 10.1016/j.chembiol.2009.05.008. Chem Biol. 2009. PMID: 19549601

3

The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.

Kryza T, Bock N, Lovell S, Rockstroh A, Lehman ML, Lesner A, Panchadsaram J, Silva LM, Srinivasan S, Snell CE, Williams ED, Fazli L, Gleave M, Batra J, Nelson C, Tate EW, Harris J, Hooper JD, Clements JA. Kryza T, et al. Mol Oncol. 2020 Jan;14(1):105-128. doi: 10.1002/1878-0261.12587. Epub 2019 Nov 28. Mol Oncol. 2020. PMID: 31630475 Free PMC article.

4

KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer.

Tse BW, Kryza T, Yeh MC, Dong Y, Sokolowski KA, Walpole C, Dreyer T, Felber J, Harris J, Magdolen V, Russell PJ, Clements JA. Tse BW, et al. Cancers (Basel). 2020 Nov 24;12(12):3501. doi: 10.3390/cancers12123501. Cancers (Basel). 2020. PMID: 33255452 Free PMC article.

5

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.

de Veer SJ, Swedberg JE, Parker EA, Harris JM. de Veer SJ, et al. Among authors: harris jm. Biol Chem. 2012 Apr;393(5):331-41. doi: 10.1515/bc-2011-250. Biol Chem. 2012. PMID: 22505516 Free article.

6

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells.

Sanchez WY, de Veer SJ, Swedberg JE, Hong EJ, Reid JC, Walsh TP, Hooper JD, Hammond GL, Clements JA, Harris JM. Sanchez WY, et al. Among authors: harris jm. Endocrinology. 2012 Jul;153(7):3179-89. doi: 10.1210/en.2012-1011. Epub 2012 Apr 30. Endocrinology. 2012. PMID: 22547569 Free article.

7

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

de Veer SJ, Ukolova SS, Munro CA, Swedberg JE, Buckle AM, Harris JM. de Veer SJ, et al. Among authors: harris jm. Biopolymers. 2013 Mar 11. doi: 10.1002/peps.22231. Online ahead of print. Biopolymers. 2013. PMID: 23494567

8

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

de Veer SJ, Ukolova SS, Munro CA, Swedberg JE, Buckle AM, Harris JM. de Veer SJ, et al. Among authors: harris jm. Biopolymers. 2013 Sep;100(5):510-8. doi: 10.1002/bip.22231. Biopolymers. 2013. PMID: 24078181

9

Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum.

de Veer SJ, Furio L, Swedberg JE, Munro CA, Brattsand M, Clements JA, Hovnanian A, Harris JM. de Veer SJ, et al. Among authors: harris jm. J Invest Dermatol. 2017 Feb;137(2):430-439. doi: 10.1016/j.jid.2016.09.017. Epub 2016 Sep 30. J Invest Dermatol. 2017. PMID: 27697464 Free article.

10

Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II.

Swedberg JE, Ghani HA, Harris JM, de Veer SJ, Craik DJ. Swedberg JE, et al. Among authors: harris jm. ACS Med Chem Lett. 2018 Nov 21;9(12):1258-1262. doi: 10.1021/acsmedchemlett.8b00422. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613336 Free PMC article.

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