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Rapalogs and mTOR inhibitors as anti-aging therapeutics.
Lamming DW, Ye L, Sabatini DM, Baur JA. Lamming DW, et al. Among authors: sabatini dm. J Clin Invest. 2013 Mar;123(3):980-9. doi: 10.1172/JCI64099. Epub 2013 Mar 1. J Clin Invest. 2013. PMID: 23454761 Free PMC article. Review.
An expanding role for mTOR in cancer.
Guertin DA, Sabatini DM. Guertin DA, et al. Among authors: sabatini dm. Trends Mol Med. 2005 Aug;11(8):353-61. doi: 10.1016/j.molmed.2005.06.007. Trends Mol Med. 2005. PMID: 16002336 Review.
Defining the role of mTOR in cancer.
Guertin DA, Sabatini DM. Guertin DA, et al. Among authors: sabatini dm. Cancer Cell. 2007 Jul;12(1):9-22. doi: 10.1016/j.ccr.2007.05.008. Cancer Cell. 2007. PMID: 17613433 Free article. Review.
The pharmacology of mTOR inhibition.
Guertin DA, Sabatini DM. Guertin DA, et al. Among authors: sabatini dm. Sci Signal. 2009 Apr 21;2(67):pe24. doi: 10.1126/scisignal.267pe24. Sci Signal. 2009. PMID: 19383975
mTOR signaling at a glance.
Laplante M, Sabatini DM. Laplante M, et al. Among authors: sabatini dm. J Cell Sci. 2009 Oct 15;122(Pt 20):3589-94. doi: 10.1242/jcs.051011. J Cell Sci. 2009. PMID: 19812304 Free PMC article. Review. No abstract available.
mTOR and cancer: many loops in one pathway.
Efeyan A, Sabatini DM. Efeyan A, et al. Among authors: sabatini dm. Curr Opin Cell Biol. 2010 Apr;22(2):169-76. doi: 10.1016/j.ceb.2009.10.007. Epub 2009 Nov 27. Curr Opin Cell Biol. 2010. PMID: 19945836 Free PMC article.
A radical role for TOR in longevity.
Lamming DW, Sabatini DM. Lamming DW, et al. Among authors: sabatini dm. Cell Metab. 2011 Jun 8;13(6):617-8. doi: 10.1016/j.cmet.2011.05.006. Cell Metab. 2011. PMID: 21641542 Free PMC article.
289 results