Parent AA - Search Results

1

Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α.

Srinivasan S, Nwachukwu JC, Parent AA, Cavett V, Nowak J, Hughes TS, Kojetin DJ, Katzenellenbogen JA, Nettles KW. Srinivasan S, et al. Among authors: parent aa. Nat Chem Biol. 2013 May;9(5):326-32. doi: 10.1038/nchembio.1214. Epub 2013 Mar 24. Nat Chem Biol. 2013. PMID: 23524984 Free PMC article.

2

Coupling of receptor conformation and ligand orientation determine graded activity.

Bruning JB, Parent AA, Gil G, Zhao M, Nowak J, Pace MC, Smith CL, Afonine PV, Adams PD, Katzenellenbogen JA, Nettles KW. Bruning JB, et al. Among authors: parent aa. Nat Chem Biol. 2010 Nov;6(11):837-43. doi: 10.1038/nchembio.451. Epub 2010 Oct 10. Nat Chem Biol. 2010. PMID: 20924370 Free PMC article.

3

Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.

Nwachukwu JC, Srinivasan S, Bruno NE, Parent AA, Hughes TS, Pollock JA, Gjyshi O, Cavett V, Nowak J, Garcia-Ordonez RD, Houtman R, Griffin PR, Kojetin DJ, Katzenellenbogen JA, Conkright MD, Nettles KW. Nwachukwu JC, et al. Among authors: parent aa. Elife. 2014 Apr 25;3:e02057. doi: 10.7554/eLife.02057. Elife. 2014. PMID: 24771768 Free PMC article.

4

Blocking estrogen signaling after the hormone: pyrimidine-core inhibitors of estrogen receptor-coactivator binding.

Parent AA, Gunther JR, Katzenellenbogen JA. Parent AA, et al. J Med Chem. 2008 Oct 23;51(20):6512-30. doi: 10.1021/jm800698b. Epub 2008 Sep 12. J Med Chem. 2008. PMID: 18785725 Free PMC article.

5

Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer.

Pollock JA, Wardell SE, Parent AA, Stagg DB, Ellison SJ, Alley HM, Chao CA, Lawrence SA, Stice JP, Spasojevic I, Baker JG, Kim SH, McDonnell DP, Katzenellenbogen JA, Norris JD. Pollock JA, et al. Among authors: parent aa. Nat Chem Biol. 2016 Oct;12(10):795-801. doi: 10.1038/nchembio.2131. Epub 2016 Aug 8. Nat Chem Biol. 2016. PMID: 27501397 Free PMC article.

6

Alternative inhibition of androgen receptor signaling: peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors.

Gunther JR, Parent AA, Katzenellenbogen JA. Gunther JR, et al. Among authors: parent aa. ACS Chem Biol. 2009 Jun 19;4(6):435-40. doi: 10.1021/cb900043e. ACS Chem Biol. 2009. PMID: 19441848 Free PMC article.

7

π-π interaction energies as determinants of the photodimerization of mono-, di-, and triazastilbenes.

Parent AA, Ess DH, Katzenellenbogen JA. Parent AA, et al. J Org Chem. 2014 Jun 20;79(12):5448-62. doi: 10.1021/jo500457n. Epub 2014 May 28. J Org Chem. 2014. PMID: 24837276 Free PMC article.

8

Mechanistic analysis of the photocycloaddition of silyl-tethered alkenes.

Fleming SA, Parent AA, Parent EE, Pincock JA, Renault L. Fleming SA, et al. Among authors: parent aa, parent ee. J Org Chem. 2007 Dec 7;72(25):9464-70. doi: 10.1021/jo7014664. Epub 2007 Nov 13. J Org Chem. 2007. PMID: 17997569

9

Conformational analysis of ketolide, conformations of RU 004 in solution and bound to bacterial ribosomes.

Bertho G, Gharbi-Benarous J, Delaforge M, Lang C, Parent A, Girault JP. Bertho G, et al. J Med Chem. 1998 Aug 27;41(18):3373-86. doi: 10.1021/jm970852i. J Med Chem. 1998. PMID: 9719590

10

Conformations in solution and bound to bacterial ribosomes of ketolides, HMR 3647 (telithromycin) and RU 72366: a new class of highly potent antibacterials.

Evrard-Todeschi N, Gharbi-Benarous J, Gaillet C, Verdier L, Bertho G, Lang C, Parent A, Girault JP. Evrard-Todeschi N, et al. Bioorg Med Chem. 2000 Jul;8(7):1579-97. doi: 10.1016/s0968-0896(00)00091-2. Bioorg Med Chem. 2000. PMID: 10976506

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