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Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion.
Egan ES, Jiang RH, Moechtar MA, Barteneva NS, Weekes MP, Nobre LV, Gygi SP, Paulo JA, Frantzreb C, Tani Y, Takahashi J, Watanabe S, Goldberg J, Paul AS, Brugnara C, Root DE, Wiegand RC, Doench JG, Duraisingh MT. Egan ES, et al. Among authors: brugnara c. Science. 2015 May 8;348(6235):711-4. doi: 10.1126/science.aaa3526. Science. 2015. PMID: 25954012 Free PMC article.
Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum.
Egan ES, Weekes MP, Kanjee U, Manzo J, Srinivasan A, Lomas-Francis C, Westhoff C, Takahashi J, Tanaka M, Watanabe S, Brugnara C, Gygi SP, Tani Y, Duraisingh MT. Egan ES, et al. Among authors: brugnara c. Commun Biol. 2018 May 3;1:45. doi: 10.1038/s42003-018-0046-2. eCollection 2018. Commun Biol. 2018. PMID: 30271928 Free PMC article.
Plasmodium vivax infection compromises reticulocyte stability.
Clark MA, Kanjee U, Rangel GW, Chery L, Mascarenhas A, Gomes E, Rathod PK, Brugnara C, Ferreira MU, Duraisingh MT. Clark MA, et al. Among authors: brugnara c. Nat Commun. 2021 Mar 12;12(1):1629. doi: 10.1038/s41467-021-21886-x. Nat Commun. 2021. PMID: 33712609 Free PMC article.
Purinergic signaling is essential for full Psickle activation by hypoxia and by normoxic acid pH in mature human sickle red cells and in vitro-differentiated cultured human sickle reticulocytes.
Vandorpe DH, Rivera A, Ganter M, Dankwa S, Wohlgemuth JG, Dlott JS, Snyder LM, Brugnara C, Duraisingh M, Alper SL. Vandorpe DH, et al. Among authors: brugnara c. Pflugers Arch. 2022 May;474(5):553-565. doi: 10.1007/s00424-022-02665-z. Epub 2022 Feb 16. Pflugers Arch. 2022. PMID: 35169901
Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts.
Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, Heggers SK, Vogin G, Chen W, Chen C, Campagna DR, Brugnara C, Zhou Y, Ebert BL, Danial NN, Fleming MD, Ward DM, Campanella M, Dailey HA, Kaplan J, Paw BH. Shah DI, et al. Among authors: brugnara c. Nature. 2012 Nov 22;491(7425):608-12. doi: 10.1038/nature11536. Epub 2012 Nov 7. Nature. 2012. PMID: 23135403 Free PMC article.
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.
Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, Zon LI. Donovan A, et al. Among authors: brugnara c. Nature. 2000 Feb 17;403(6771):776-81. doi: 10.1038/35001596. Nature. 2000. PMID: 10693807
Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Wu Y, Zeng J, Roscoe BP, Liu P, Yao Q, Lazzarotto CR, Clement K, Cole MA, Luk K, Baricordi C, Shen AH, Ren C, Esrick EB, Manis JP, Dorfman DM, Williams DA, Biffi A, Brugnara C, Biasco L, Brendel C, Pinello L, Tsai SQ, Wolfe SA, Bauer DE. Wu Y, et al. Among authors: brugnara c. Nat Med. 2019 May;25(5):776-783. doi: 10.1038/s41591-019-0401-y. Epub 2019 Mar 25. Nat Med. 2019. PMID: 30911135 Free PMC article.
291 results