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X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction.
Zhang P, Munier JJ, Wiese CB, Vergnes L, Link JC, Abbasi F, Ronquillo E, Scheker K, Muñoz A, Kuang YL, Theusch E, Lu M, Sanchez G, Oni-Orisan A, Iribarren C, McPhaul MJ, Nomura DK, Knowles JW, Krauss RM, Medina MW, Reue K. Zhang P, et al. Among authors: medina mw. Nat Commun. 2024 Jul 2;15(1):5571. doi: 10.1038/s41467-024-49764-2. Nat Commun. 2024. PMID: 38956041 Free PMC article.
Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response.
Theusch E, Ting FY, Qin Y, Stevens K, Naidoo D, King SM, Yang N, Orr J, Han BY, Cyster JG, Chen YI, Rotter JI, Krauss RM, Medina MW. Theusch E, et al. Among authors: medina mw. bioRxiv [Preprint]. 2023 Jun 15:2023.06.14.544860. doi: 10.1101/2023.06.14.544860. bioRxiv. 2023. Update in: Genome Med. 2024 Jul 26;16(1):93. doi: 10.1186/s13073-024-01366-9 PMID: 37397985 Free PMC article. Updated. Preprint.
Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease.
Muñoz A, Theusch E, Kuang YL, Nalula G, Peaslee C, Dorlhiac G, Landry MP, Streets A, Krauss RM, Iribarren C, Mattis AN, Medina MW. Muñoz A, et al. Among authors: medina mw. Cell Mol Gastroenterol Hepatol. 2022;14(5):1174-1176.e6. doi: 10.1016/j.jcmgh.2022.07.009. Epub 2022 Jul 19. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35863744 Free PMC article. No abstract available.
A gene-diet interaction controlling relative intake of dietary carbohydrates and fats.
Nelson NG, Wu L, Maier MT, Lam D, Cheang R, Alba D, Huang A, Neumann DA, Hill T, Vagena E, Barsh GS, Medina MW, Krauss RM, Koliwad SK, Xu AW. Nelson NG, et al. Among authors: medina mw. Mol Metab. 2022 Apr;58:101442. doi: 10.1016/j.molmet.2022.101442. Epub 2022 Jan 19. Mol Metab. 2022. PMID: 35051651 Free PMC article.
A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts.
Veturi Y, Lucas A, Bradford Y, Hui D, Dudek S, Theusch E, Verma A, Miller JE, Kullo I, Hakonarson H, Sleiman P, Schaid D, Stein CM, Edwards DRV, Feng Q, Wei WQ, Medina MW, Krauss RM, Hoffmann TJ, Risch N, Voight BF, Rader DJ, Ritchie MD. Veturi Y, et al. Among authors: medina mw. Nat Genet. 2021 Jul;53(7):972-981. doi: 10.1038/s41588-021-00879-y. Epub 2021 Jun 17. Nat Genet. 2021. PMID: 34140684 Free PMC article.
63 results