Schröter T - Search Results

1

Synthesis and biological evaluation of urea derivatives as highly potent and selective rho kinase inhibitors.

Yin Y, Lin L, Ruiz C, Khan S, Cameron MD, Grant W, Pocas J, Eid N, Park H, Schröter T, Lograsso PV, Feng Y. Yin Y, et al. Among authors: schroter t. J Med Chem. 2013 May 9;56(9):3568-81. doi: 10.1021/jm400062r. Epub 2013 Apr 25. J Med Chem. 2013. PMID: 23570561

2

Structure-activity relationships, and drug metabolism and pharmacokinetic properties for indazole piperazine and indazole piperidine inhibitors of ROCK-II.

Feng Y, Cameron MD, Frackowiak B, Griffin E, Lin L, Ruiz C, Schröter T, LoGrasso P. Feng Y, et al. Among authors: schroter t. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2355-60. doi: 10.1016/j.bmcl.2006.12.043. Epub 2006 Dec 21. Bioorg Med Chem Lett. 2007. PMID: 17368019

3

Detection of myosin light chain phosphorylation--a cell-based assay for screening Rho-kinase inhibitors.

Schröter T, Griffin E, Weiser A, Feng Y, LoGrasso P. Schröter T, et al. Biochem Biophys Res Commun. 2008 Sep 19;374(2):356-60. doi: 10.1016/j.bbrc.2008.07.028. Epub 2008 Jul 16. Biochem Biophys Res Commun. 2008. PMID: 18638453

4

Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors.

Feng Y, Yin Y, Weiser A, Griffin E, Cameron MD, Lin L, Ruiz C, Schürer SC, Inoue T, Rao PV, Schröter T, Lograsso P. Feng Y, et al. Among authors: schroter t. J Med Chem. 2008 Nov 13;51(21):6642-5. doi: 10.1021/jm800986w. Epub 2008 Oct 4. J Med Chem. 2008. PMID: 18834107 Free PMC article.

5

Chroman-3-amides as potent Rho kinase inhibitors.

Chen YT, Bannister TD, Weiser A, Griffin E, Lin L, Ruiz C, Cameron MD, Schürer S, Duckett D, Schröter T, LoGrasso P, Feng Y. Chen YT, et al. Among authors: schroter t. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6406-9. doi: 10.1016/j.bmcl.2008.10.080. Epub 2008 Oct 22. Bioorg Med Chem Lett. 2008. PMID: 18990570

6

Benzimidazole- and benzoxazole-based inhibitors of Rho kinase.

Sessions EH, Yin Y, Bannister TD, Weiser A, Griffin E, Pocas J, Cameron MD, Ruiz C, Lin L, Schürer SC, Schröter T, LoGrasso P, Feng Y. Sessions EH, et al. Among authors: schroter t. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6390-3. doi: 10.1016/j.bmcl.2008.10.095. Epub 2008 Oct 25. Bioorg Med Chem Lett. 2008. PMID: 18996009

7

Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors.

Yin Y, Lin L, Ruiz C, Cameron MD, Pocas J, Grant W, Schröter T, Chen W, Duckett D, Schürer S, Lograsso P, Feng Y. Yin Y, et al. Among authors: schroter t. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6686-90. doi: 10.1016/j.bmcl.2009.09.115. Epub 2009 Oct 3. Bioorg Med Chem Lett. 2009. PMID: 19837589

8

The development of benzimidazoles as selective rho kinase inhibitors.

Sessions EH, Smolinski M, Wang B, Frackowiak B, Chowdhury S, Yin Y, Chen YT, Ruiz C, Lin L, Pocas J, Schröter T, Cameron MD, LoGrasso P, Feng Y, Bannister TD. Sessions EH, et al. Among authors: schroter t. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1939-43. doi: 10.1016/j.bmcl.2010.01.124. Epub 2010 Feb 1. Bioorg Med Chem Lett. 2010. PMID: 20167489

9

Tetrahydroisoquinoline derivatives as highly selective and potent Rho kinase inhibitors.

Fang X, Yin Y, Chen YT, Yao L, Wang B, Cameron MD, Lin L, Khan S, Ruiz C, Schröter T, Grant W, Weiser A, Pocas J, Pachori A, Schürer S, Lograsso P, Feng Y. Fang X, et al. Among authors: schroter t. J Med Chem. 2010 Aug 12;53(15):5727-37. doi: 10.1021/jm100579r. J Med Chem. 2010. PMID: 20684608

10

Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors.

Fang X, Chen YT, Sessions EH, Chowdhury S, Vojkovsky T, Yin Y, Pocas JR, Grant W, Schröter T, Lin L, Ruiz C, Cameron MD, LoGrasso P, Bannister TD, Feng Y. Fang X, et al. Among authors: schroter t. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1844-8. doi: 10.1016/j.bmcl.2011.01.039. Epub 2011 Jan 14. Bioorg Med Chem Lett. 2011. PMID: 21349713

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