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Page 1
Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus.
Webb R, Wren JD, Jeffries M, Kelly JA, Kaufman KM, Tang Y, Frank MB, Merrill J, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Alarcón GS, Vilá LM, Alarcón-Riquelme ME, James JA, Vyse TJ, Moser KL, Gaffney PM, Gilkeson GS, Harley JB, Sawalha AH. Webb R, et al. Among authors: sawalha ah. Arthritis Rheum. 2009 Apr;60(4):1076-84. doi: 10.1002/art.24360. Arthritis Rheum. 2009. PMID: 19333917 Free PMC article.
Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.
Sanchez E, Webb RD, Rasmussen A, Kelly JA, Riba L, Kaufman KM, Garcia-de la Torre I, Moctezuma JF, Maradiaga-Ceceña MA, Cardiel-Rios MH, Acevedo E, Cucho-Venegas M, Garcia MA, Gamron S, Pons-Estel BA, Vasconcelos C, Martin J, Tusié-Luna T, Harley JB, Richardson B, Sawalha AH, Alarcón-Riquelme ME. Sanchez E, et al. Among authors: sawalha ah. Arthritis Rheum. 2010 Dec;62(12):3722-9. doi: 10.1002/art.27753. Arthritis Rheum. 2010. PMID: 20848568 Free PMC article.
Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.
Webb R, Kelly JA, Somers EC, Hughes T, Kaufman KM, Sanchez E, Nath SK, Bruner G, Alarcón-Riquelme ME, Gilkeson GS, Kamen DL, Richardson BC, Harley JB, Sawalha AH. Webb R, et al. Among authors: sawalha ah. Ann Rheum Dis. 2011 Jan;70(1):151-6. doi: 10.1136/ard.2010.141697. Epub 2010 Sep 29. Ann Rheum Dis. 2011. PMID: 20881011 Free PMC article.
Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
Sánchez E, Comeau ME, Freedman BI, Kelly JA, Kaufman KM, Langefeld CD, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Vilá LM, Merrill JT, Tsao BP, Kamen DL, Gilkeson GS, James JA, Vyse TJ; International Consortium on the Genetics of Systemic Lupus Erythematosus; Gaffney PM, Jacob CO, Niewold TB, Richardson BC, Harley JB, Alarcón-Riquelme ME, Sawalha AH. Sánchez E, et al. Among authors: sawalha ah. Arthritis Rheum. 2011 Nov;63(11):3493-501. doi: 10.1002/art.30563. Arthritis Rheum. 2011. PMID: 21792837 Free PMC article.
Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus.
Hughes T, Adler A, Kelly JA, Kaufman KM, Williams AH, Langefeld CD, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Boackle SA, Stevens AM, Reveille JD, Sanchez E, Martín J, Niewold TB, Vilá LM, Scofield RH, Gilkeson GS, Gaffney PM, Criswell LA, Moser KL, Merrill JT, Jacob CO, Tsao BP, James JA, Vyse TJ, Alarcón-Riquelme ME; BIOLUPUS Network; Harley JB, Richardson BC, Sawalha AH. Hughes T, et al. Among authors: sawalha ah. Arthritis Rheum. 2012 Feb;64(2):485-92. doi: 10.1002/art.33354. Arthritis Rheum. 2012. PMID: 21952918 Free PMC article.
210 results