Homan KT - Search Results

1

Insights into congenital stationary night blindness based on the structure of G90D rhodopsin.

Singhal A, Ostermaier MK, Vishnivetskiy SA, Panneels V, Homan KT, Tesmer JJ, Veprintsev D, Deupi X, Gurevich VV, Schertler GF, Standfuss J. Singhal A, et al. Among authors: homan kt. EMBO Rep. 2013 Jun;14(6):520-6. doi: 10.1038/embor.2013.44. Epub 2013 Apr 12. EMBO Rep. 2013. PMID: 23579341 Free PMC article.

2

Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding.

Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, Sligar SG, Tesmer JJ, Schertler GF, Standfuss J, Gurevich VV. Vishnivetskiy SA, et al. Among authors: homan kt. Cell Signal. 2013 Nov;25(11):2155-62. doi: 10.1016/j.cellsig.2013.07.009. Epub 2013 Jul 17. Cell Signal. 2013. PMID: 23872075 Free PMC article.

3

C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor.

Azevedo AW, Doan T, Moaven H, Sokal I, Baameur F, Vishnivetskiy SA, Homan KT, Tesmer JJ, Gurevich VV, Chen J, Rieke F. Azevedo AW, et al. Among authors: homan kt. Elife. 2015 Apr 24;4:e05981. doi: 10.7554/eLife.05981. Elife. 2015. PMID: 25910054 Free PMC article.

4

Regulation of G protein-coupled receptor kinases by phospholipids.

Homan KT, Glukhova A, Tesmer JJ. Homan KT, et al. Curr Med Chem. 2013;20(1):39-46. Curr Med Chem. 2013. PMID: 23151001 Review.

5

Substrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1).

Orban T, Huang CC, Homan KT, Jastrzebska B, Tesmer JJ, Palczewski K. Orban T, et al. Among authors: homan kt. Biochemistry. 2012 Apr 24;51(16):3404-11. doi: 10.1021/bi300295y. Epub 2012 Apr 11. Biochemistry. 2012. PMID: 22480180 Free PMC article.

6

Structural insights into G protein-coupled receptor kinase function.

Homan KT, Tesmer JJ. Homan KT, et al. Curr Opin Cell Biol. 2014 Apr;27:25-31. doi: 10.1016/j.ceb.2013.10.009. Epub 2013 Nov 26. Curr Opin Cell Biol. 2014. PMID: 24680427 Free PMC article. Review.

7

Molecular basis for small molecule inhibition of G protein-coupled receptor kinases.

Homan KT, Tesmer JJ. Homan KT, et al. ACS Chem Biol. 2015 Jan 16;10(1):246-56. doi: 10.1021/cb5003976. Epub 2014 Jul 14. ACS Chem Biol. 2015. PMID: 24984143 Free PMC article. Review.

8

G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).

Li L, Homan KT, Vishnivetskiy SA, Manglik A, Tesmer JJ, Gurevich VV, Gurevich EV. Li L, et al. Among authors: homan kt. J Biol Chem. 2015 Apr 24;290(17):10775-90. doi: 10.1074/jbc.M115.644773. Epub 2015 Mar 13. J Biol Chem. 2015. PMID: 25770216 Free PMC article.

9

G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro.

Inagaki S, Ghirlando R, Vishnivetskiy SA, Homan KT, White JF, Tesmer JJ, Gurevich VV, Grisshammer R. Inagaki S, et al. Among authors: homan kt. Biochemistry. 2015 Jul 21;54(28):4320-9. doi: 10.1021/acs.biochem.5b00285. Epub 2015 Jul 8. Biochemistry. 2015. PMID: 26120872 Free PMC article.

10

Membrane orientation of Gα(i)β(1)γ(2) and Gβ(1)γ(2) determined via combined vibrational spectroscopic studies.

Yang P, Boughton A, Homan KT, Tesmer JJ, Chen Z. Yang P, et al. Among authors: homan kt. J Am Chem Soc. 2013 Apr 3;135(13):5044-51. doi: 10.1021/ja3116026. Epub 2013 Mar 21. J Am Chem Soc. 2013. PMID: 23461393 Free PMC article.

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