Yang P - Search Results

1

Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication.

Nasheri N, Joyce M, Rouleau Y, Yang P, Yao S, Tyrrell DL, Pezacki JP. Nasheri N, et al. Among authors: yang p. Chem Biol. 2013 Apr 18;20(4):570-82. doi: 10.1016/j.chembiol.2013.03.014. Chem Biol. 2013. PMID: 23601646

2

Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes.

Yang PY, Liu K, Zhang C, Chen GY, Shen Y, Ngai MH, Lear MJ, Yao SQ. Yang PY, et al. Chem Asian J. 2011 Oct 4;6(10):2762-75. doi: 10.1002/asia.201100306. Epub 2011 Jul 8. Chem Asian J. 2011. PMID: 21744505

3

Click-based synthesis and proteomic profiling of lipstatin analogues.

Ngai MH, Yang PY, Liu K, Shen Y, Wenk MR, Yao SQ, Lear MJ. Ngai MH, et al. Chem Commun (Camb). 2010 Nov 28;46(44):8335-7. doi: 10.1039/c0cc01276a. Epub 2010 Jun 24. Chem Commun (Camb). 2010. PMID: 20577697

4

Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities.

Yang PY, Liu K, Ngai MH, Lear MJ, Wenk MR, Yao SQ. Yang PY, et al. J Am Chem Soc. 2010 Jan 20;132(2):656-66. doi: 10.1021/ja907716f. J Am Chem Soc. 2010. PMID: 20028024

5

"Click" synthesis of small-molecule inhibitors targeting caspases.

Ng SL, Yang PY, Chen KY, Srinivasan R, Yao SQ. Ng SL, et al. Org Biomol Chem. 2008 Mar 7;6(5):844-7. doi: 10.1039/b718304f. Epub 2008 Feb 4. Org Biomol Chem. 2008. PMID: 18292873

6

Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei.

Yang PY, Wang M, He CY, Yao SQ. Yang PY, et al. Chem Commun (Camb). 2012 Jan 21;48(6):835-7. doi: 10.1039/c1cc16178d. Epub 2011 Nov 28. Chem Commun (Camb). 2012. PMID: 22124229

7

Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.

Yang PY, Wang M, Li L, Wu H, He CY, Yao SQ. Yang PY, et al. Chemistry. 2012 May 21;18(21):6528-41. doi: 10.1002/chem.201103322. Epub 2012 Apr 4. Chemistry. 2012. PMID: 22488888

8

Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent.

Yang PY, Wang M, Liu K, Ngai MH, Sheriff O, Lear MJ, Sze SK, He CY, Yao SQ. Yang PY, et al. Chemistry. 2012 Jul 2;18(27):8403-13. doi: 10.1002/chem.201200482. Epub 2012 Jun 1. Chemistry. 2012. PMID: 22674877

9

High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening.

Srinivasan R, Tan LP, Wu H, Yang PY, Kalesh KA, Yao SQ. Srinivasan R, et al. Org Biomol Chem. 2009 May 7;7(9):1821-8. doi: 10.1039/b902338k. Epub 2009 Mar 11. Org Biomol Chem. 2009. PMID: 19590777

10

A peptide aldehyde microarray for high-throughput profiling of cellular events.

Wu H, Ge J, Yang PY, Wang J, Uttamchandani M, Yao SQ. Wu H, et al. J Am Chem Soc. 2011 Feb 16;133(6):1946-54. doi: 10.1021/ja109597v. Epub 2011 Jan 19. J Am Chem Soc. 2011. PMID: 21247160

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