McManus KJ - Search Results

1

Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis.

Thompson LL, Guppy BJ, Sawchuk L, Davie JR, McManus KJ. Thompson LL, et al. Among authors: mcmanus kj. Cancer Metastasis Rev. 2013 Dec;32(3-4):363-76. doi: 10.1007/s10555-013-9434-8. Cancer Metastasis Rev. 2013. PMID: 23609752 Review.

2

An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development.

van Pel DM, Barrett IJ, Shimizu Y, Sajesh BV, Guppy BJ, Pfeifer T, McManus KJ, Hieter P. van Pel DM, et al. Among authors: mcmanus kj. PLoS Genet. 2013;9(1):e1003254. doi: 10.1371/journal.pgen.1003254. Epub 2013 Jan 31. PLoS Genet. 2013. PMID: 23382697 Free PMC article.

3

Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells.

Sajesh BV, Lichtensztejn Z, McManus KJ. Sajesh BV, et al. Among authors: mcmanus kj. BMC Cancer. 2013 Aug 20;13:391. doi: 10.1186/1471-2407-13-391. BMC Cancer. 2013. PMID: 23962039 Free PMC article.

4

Synthetic genetic targeting of genome instability in cancer.

Sajesh BV, Guppy BJ, McManus KJ. Sajesh BV, et al. Among authors: mcmanus kj. Cancers (Basel). 2013 Jun 24;5(3):739-61. doi: 10.3390/cancers5030739. Cancers (Basel). 2013. PMID: 24202319 Free PMC article.

5

Mitotic accumulation of dimethylated lysine 79 of histone H3 is important for maintaining genome integrity during mitosis in human cells.

Guppy BJ, McManus KJ. Guppy BJ, et al. Among authors: mcmanus kj. Genetics. 2015 Feb;199(2):423-33. doi: 10.1534/genetics.114.172874. Epub 2014 Dec 22. Genetics. 2015. PMID: 25533199 Free PMC article.

6

A novel multiplexed, image-based approach to detect phenotypes that underlie chromosome instability in human cells.

Thompson LL, McManus KJ. Thompson LL, et al. Among authors: mcmanus kj. PLoS One. 2015 Apr 20;10(4):e0123200. doi: 10.1371/journal.pone.0123200. eCollection 2015. PLoS One. 2015. PMID: 25893404 Free PMC article.

7

The steroid receptor RNA activator protein (SRAP) controls cancer cell migration/motility.

Yan Y, Cooper C, Hamedani MK, Guppy B, Xu W, Tsuyuki D, Zhang C, Nugent Z, Blanchard A, Davie JR, McManus K, Murphy LC, Myal Y, Leygue E. Yan Y, et al. FEBS Lett. 2015 Dec 21;589(24 Pt B):4010-8. doi: 10.1016/j.febslet.2015.11.007. Epub 2015 Nov 17. FEBS Lett. 2015. PMID: 26581859 Free article.

8

The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer.

McAndrew EN, McManus KJ. McAndrew EN, et al. Among authors: mcmanus kj. Genes Chromosomes Cancer. 2017 Jul;56(7):513-523. doi: 10.1002/gcc.22458. Epub 2017 Apr 4. Genes Chromosomes Cancer. 2017. PMID: 28295846 Review.

9

Synthetic lethal targeting of RNF20 through PARP1 silencing and inhibition.

Guppy BJ, McManus KJ. Guppy BJ, et al. Among authors: mcmanus kj. Cell Oncol (Dordr). 2017 Jun;40(3):281-292. doi: 10.1007/s13402-017-0323-y. Epub 2017 May 1. Cell Oncol (Dordr). 2017. PMID: 28462496

10

KIF11 silencing and inhibition induces chromosome instability that may contribute to cancer.

Asbaghi Y, Thompson LL, Lichtensztejn Z, McManus KJ. Asbaghi Y, et al. Among authors: mcmanus kj. Genes Chromosomes Cancer. 2017 Sep;56(9):668-680. doi: 10.1002/gcc.22471. Epub 2017 Jun 15. Genes Chromosomes Cancer. 2017. PMID: 28510357

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