Scott EE - Search Results

1

Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR.

Estrada DF, Laurence JS, Scott EE. Estrada DF, et al. Among authors: scott ee. J Biol Chem. 2013 Jun 7;288(23):17008-17018. doi: 10.1074/jbc.M113.468926. Epub 2013 Apr 25. J Biol Chem. 2013. PMID: 23620596 Free PMC article.

2

Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding.

Scott EE, White MA, He YA, Johnson EF, Stout CD, Halpert JR. Scott EE, et al. J Biol Chem. 2004 Jun 25;279(26):27294-301. doi: 10.1074/jbc.M403349200. Epub 2004 Apr 20. J Biol Chem. 2004. PMID: 15100217 Free article.

3

Structure of the human lung cytochrome P450 2A13.

Smith BD, Sanders JL, Porubsky PR, Lushington GH, Stout CD, Scott EE. Smith BD, et al. Among authors: scott ee. J Biol Chem. 2007 Jun 8;282(23):17306-13. doi: 10.1074/jbc.M702361200. Epub 2007 Apr 11. J Biol Chem. 2007. PMID: 17428784 Free article.

4

Key residues controlling phenacetin metabolism by human cytochrome P450 2A enzymes.

DeVore NM, Smith BD, Urban MJ, Scott EE. DeVore NM, et al. Among authors: scott ee. Drug Metab Dispos. 2008 Dec;36(12):2582-90. doi: 10.1124/dmd.108.023770. Epub 2008 Sep 8. Drug Metab Dispos. 2008. PMID: 18779312 Free PMC article.

5

Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates.

Porubsky PR, Meneely KM, Scott EE. Porubsky PR, et al. Among authors: scott ee. J Biol Chem. 2008 Nov 28;283(48):33698-707. doi: 10.1074/jbc.M805999200. Epub 2008 Sep 24. J Biol Chem. 2008. PMID: 18818195 Free PMC article.

6

Key residues controlling binding of diverse ligands to human cytochrome P450 2A enzymes.

DeVore NM, Smith BD, Wang JL, Lushington GH, Scott EE. DeVore NM, et al. Among authors: scott ee. Drug Metab Dispos. 2009 Jun;37(6):1319-27. doi: 10.1124/dmd.109.026765. Epub 2009 Feb 27. Drug Metab Dispos. 2009. PMID: 19251817 Free PMC article.

7

Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode.

Porubsky PR, Battaile KP, Scott EE. Porubsky PR, et al. Among authors: scott ee. J Biol Chem. 2010 Jul 16;285(29):22282-90. doi: 10.1074/jbc.M110.109017. Epub 2010 May 12. J Biol Chem. 2010. PMID: 20463018 Free PMC article.

8

Crystal structure of histamine dehydrogenase from Nocardioides simplex.

Reed T, Lushington GH, Xia Y, Hirakawa H, Travis DM, Mure M, Scott EE, Limburg J. Reed T, et al. Among authors: scott ee. J Biol Chem. 2010 Aug 13;285(33):25782-91. doi: 10.1074/jbc.M109.084301. Epub 2010 Jun 10. J Biol Chem. 2010. PMID: 20538584 Free PMC article.

9

Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001.

DeVore NM, Scott EE. DeVore NM, et al. Among authors: scott ee. Nature. 2012 Jan 22;482(7383):116-9. doi: 10.1038/nature10743. Nature. 2012. PMID: 22266943 Free PMC article.

10

Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes.

Stephens ES, Walsh AA, Scott EE. Stephens ES, et al. Among authors: scott ee. Drug Metab Dispos. 2012 Sep;40(9):1797-802. doi: 10.1124/dmd.112.045161. Epub 2012 Jun 13. Drug Metab Dispos. 2012. PMID: 22696418 Free PMC article.

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