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Page 1
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
Lu M, Breyssens H, Salter V, Zhong S, Hu Y, Baer C, Ratnayaka I, Sullivan A, Brown NR, Endicott J, Knapp S, Kessler BM, Middleton MR, Siebold C, Jones EY, Sviderskaya EV, Cebon J, John T, Caballero OL, Goding CR, Lu X. Lu M, et al. Among authors: ratnayaka i. Cancer Cell. 2013 May 13;23(5):618-33. doi: 10.1016/j.ccr.2013.03.013. Epub 2013 Apr 25. Cancer Cell. 2013. PMID: 23623661 Free article.
SUMO-modified nuclear cyclin D1 bypasses Ras-induced senescence.
Wang XD, Lapi E, Sullivan A, Ratnayaka I, Goldin R, Hay R, Lu X. Wang XD, et al. Among authors: ratnayaka i. Cell Death Differ. 2011 Feb;18(2):304-14. doi: 10.1038/cdd.2010.101. Epub 2010 Aug 27. Cell Death Differ. 2011. PMID: 20798689 Free PMC article.
Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo.
Slee EA, Benassi B, Goldin R, Zhong S, Ratnayaka I, Blandino G, Lu X. Slee EA, et al. Among authors: ratnayaka i. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19479-84. doi: 10.1073/pnas.1005165107. Epub 2010 Oct 20. Proc Natl Acad Sci U S A. 2010. PMID: 20962274 Free PMC article.
Autophagic activity dictates the cellular response to oncogenic RAS.
Wang Y, Wang XD, Lapi E, Sullivan A, Jia W, He YW, Ratnayaka I, Zhong S, Goldin RD, Goemans CG, Tolkovsky AM, Lu X. Wang Y, et al. Among authors: ratnayaka i. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13325-30. doi: 10.1073/pnas.1120193109. Epub 2012 Jul 30. Proc Natl Acad Sci U S A. 2012. PMID: 22847423 Free PMC article.
Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development.
Sacilotto N, Monteiro R, Fritzsche M, Becker PW, Sanchez-Del-Campo L, Liu K, Pinheiro P, Ratnayaka I, Davies B, Goding CR, Patient R, Bou-Gharios G, De Val S. Sacilotto N, et al. Among authors: ratnayaka i. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11893-8. doi: 10.1073/pnas.1300805110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818617 Free PMC article.
ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63.
Tordella L, Koch S, Salter V, Pagotto A, Doondeea JB, Feller SM, Ratnayaka I, Zhong S, Goldin RD, Lozano G, McKeon FD, Tavassoli M, Fritzsche F, Huber GF, Rössle M, Moch H, Lu X. Tordella L, et al. Among authors: ratnayaka i. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17969-74. doi: 10.1073/pnas.1309362110. Epub 2013 Oct 14. Proc Natl Acad Sci U S A. 2013. PMID: 24127607 Free PMC article.
Nuclear iASPP may facilitate prostate cancer progression.
Morris EV, Cerundolo L, Lu M, Verrill C, Fritzsche F, White MJ, Thalmann GN, ten Donkelaar CS, Ratnayaka I, Salter V, Hamdy FC, Lu X, Bryant RJ. Morris EV, et al. Among authors: ratnayaka i. Cell Death Dis. 2014 Oct 23;5(10):e1492. doi: 10.1038/cddis.2014.442. Cell Death Dis. 2014. PMID: 25341046 Free PMC article.
33 results