Zhong S - Search Results

1

Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.

Lu M, Breyssens H, Salter V, Zhong S, Hu Y, Baer C, Ratnayaka I, Sullivan A, Brown NR, Endicott J, Knapp S, Kessler BM, Middleton MR, Siebold C, Jones EY, Sviderskaya EV, Cebon J, John T, Caballero OL, Goding CR, Lu X. Lu M, et al. Among authors: zhong s. Cancer Cell. 2013 May 13;23(5):618-33. doi: 10.1016/j.ccr.2013.03.013. Epub 2013 Apr 25. Cancer Cell. 2013. PMID: 23623661 Free article.

2

Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1.

O'Connor DJ, Lam EW, Griffin S, Zhong S, Leighton LC, Burbidge SA, Lu X. O'Connor DJ, et al. Among authors: zhong s. EMBO J. 1995 Dec 15;14(24):6184-92. doi: 10.1002/j.1460-2075.1995.tb00309.x. EMBO J. 1995. PMID: 8557038 Free PMC article.

3

RB regulates the stability and the apoptotic function of p53 via MDM2.

Hsieh JK, Chan FS, O'Connor DJ, Mittnacht S, Zhong S, Lu X. Hsieh JK, et al. Among authors: zhong s. Mol Cell. 1999 Feb;3(2):181-93. doi: 10.1016/s1097-2765(00)80309-3. Mol Cell. 1999. PMID: 10078201 Free article.

4

ASPP proteins specifically stimulate the apoptotic function of p53.

Samuels-Lev Y, O'Connor DJ, Bergamaschi D, Trigiante G, Hsieh JK, Zhong S, Campargue I, Naumovski L, Crook T, Lu X. Samuels-Lev Y, et al. Among authors: zhong s. Mol Cell. 2001 Oct;8(4):781-94. doi: 10.1016/s1097-2765(01)00367-7. Mol Cell. 2001. PMID: 11684014 Free article.

5

Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage.

Hsieh JK, Yap D, O'Connor DJ, Fogal V, Fallis L, Chan F, Zhong S, Lu X. Hsieh JK, et al. Among authors: zhong s. Mol Cell Biol. 2002 Jan;22(1):78-93. doi: 10.1128/MCB.22.1.78-93.2002. Mol Cell Biol. 2002. PMID: 11739724 Free PMC article.

6

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X. Bergamaschi D, et al. Among authors: zhong s. Nat Genet. 2003 Feb;33(2):162-7. doi: 10.1038/ng1070. Epub 2003 Jan 13. Nat Genet. 2003. PMID: 12524540

7

The biological response of MCF7 breast cancer cells to proteosome inhibition or gamma-radiation is unrelated to the level of p53 induction.

Fallis LH, Richards E, O'Connor DJ, Zhong S, Hsieh JK, Packham G, Lu X. Fallis LH, et al. Among authors: zhong s. Apoptosis. 1999 Apr;4(2):99-107. doi: 10.1023/a:1009614726059. Apoptosis. 1999. PMID: 14634287

8

Ser392 phosphorylation regulates the oncogenic function of mutant p53.

Yap DB, Hsieh JK, Zhong S, Heath V, Gusterson B, Crook T, Lu X. Yap DB, et al. Among authors: zhong s. Cancer Res. 2004 Jul 15;64(14):4749-54. doi: 10.1158/0008-5472.CAN-1305-2. Cancer Res. 2004. PMID: 15256442

9

Mdm2 and mdmX prevent ASPP1 and ASPP2 from stimulating p53 without targeting p53 for degradation.

Bergamaschi D, Samuels Y, Zhong S, Lu X. Bergamaschi D, et al. Among authors: zhong s. Oncogene. 2005 May 26;24(23):3836-41. doi: 10.1038/sj.onc.1208535. Oncogene. 2005. PMID: 15782125

10

Cell cycle-dependent nuclear retention of p53 by E2F1 requires phosphorylation of p53 at Ser315.

Fogal V, Hsieh JK, Royer C, Zhong S, Lu X. Fogal V, et al. Among authors: zhong s. EMBO J. 2005 Aug 3;24(15):2768-82. doi: 10.1038/sj.emboj.7600735. Epub 2005 Jul 21. EMBO J. 2005. PMID: 16037820 Free PMC article.

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