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Page 1
Targeting of a natural killer cell receptor family by a viral immunoevasin.
Berry R, Ng N, Saunders PM, Vivian JP, Lin J, Deuss FA, Corbett AJ, Forbes CA, Widjaja JM, Sullivan LC, McAlister AD, Perugini MA, Call MJ, Scalzo AA, Degli-Esposti MA, Coudert JD, Beddoe T, Brooks AG, Rossjohn J. Berry R, et al. Among authors: perugini ma. Nat Immunol. 2013 Jul;14(7):699-705. doi: 10.1038/ni.2605. Epub 2013 May 12. Nat Immunol. 2013. PMID: 23666294
A biophysical analysis of the tetratricopeptide repeat-rich mitochondrial import receptor, Tom70, reveals an elongated monomer that is inherently flexible, unstable, and unfolds via a multistate pathway.
Beddoe T, Bushell SR, Perugini MA, Lithgow T, Mulhern TD, Bottomley SP, Rossjohn J. Beddoe T, et al. Among authors: perugini ma. J Biol Chem. 2004 Nov 5;279(45):46448-54. doi: 10.1074/jbc.M405639200. Epub 2004 Aug 16. J Biol Chem. 2004. PMID: 15316022 Free article.
Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor.
Beddoe T, Chen Z, Clements CS, Ely LK, Bushell SR, Vivian JP, Kjer-Nielsen L, Pang SS, Dunstone MA, Liu YC, Macdonald WA, Perugini MA, Wilce MC, Burrows SR, Purcell AW, Tiganis T, Bottomley SP, McCluskey J, Rossjohn J. Beddoe T, et al. Among authors: perugini ma. Immunity. 2009 Jun 19;30(6):777-88. doi: 10.1016/j.immuni.2009.03.018. Epub 2009 May 21. Immunity. 2009. PMID: 19464197 Free article.
The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.
Pang SS, Berry R, Chen Z, Kjer-Nielsen L, Perugini MA, King GF, Wang C, Chew SH, La Gruta NL, Williams NK, Beddoe T, Tiganis T, Cowieson NP, Godfrey DI, Purcell AW, Wilce MC, McCluskey J, Rossjohn J. Pang SS, et al. Among authors: perugini ma. Nature. 2010 Oct 14;467(7317):844-8. doi: 10.1038/nature09448. Nature. 2010. PMID: 20944746
The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.
Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J, Vivian JP. Moradi S, et al. Among authors: perugini ma. J Biol Chem. 2015 Apr 17;290(16):10460-71. doi: 10.1074/jbc.M114.612291. Epub 2015 Mar 10. J Biol Chem. 2015. PMID: 25759384 Free PMC article.
i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.
Griffiths K, Dolezal O, Cao B, Nilsson SK, See HB, Pfleger KDG, Roche M, Gorry PR, Pow A, Viduka K, Lim K, Lu BGC, Chang DHC, Murray-Rust T, Kvansakul M, Perugini MA, Dogovski C, Doerflinger M, Zhang Y, Parisi K, Casey JL, Nuttall SD, Foley M. Griffiths K, et al. Among authors: perugini ma. J Biol Chem. 2016 Jun 10;291(24):12641-12657. doi: 10.1074/jbc.M116.721050. Epub 2016 Apr 1. J Biol Chem. 2016. PMID: 27036939 Free PMC article.
141 results