Shen J - Search Results

1

Design and synthesis of 4-(2,4,5-trifluorophenyl)butane-1,3-diamines as dipeptidyl peptidase IV inhibitors.

Zhu L, Li Y, Qiu L, Su M, Wang X, Xia C, Qu Y, Li J, Li J, Xiong B, Shen J. Zhu L, et al. Among authors: shen j. ChemMedChem. 2013 Jul;8(7):1104-16. doi: 10.1002/cmdc.201300104. Epub 2013 May 13. ChemMedChem. 2013. PMID: 23671024

2

Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: molecular docking and 3D QSAR analyses.

Liu H, Huang X, Shen J, Luo X, Li M, Xiong B, Chen G, Shen J, Yang Y, Jiang H, Chen K. Liu H, et al. Among authors: shen j. J Med Chem. 2002 Oct 24;45(22):4816-27. doi: 10.1021/jm020089e. J Med Chem. 2002. PMID: 12383007

3

Design, synthesis, and anti-inflammatory evaluation of a series of novel amino acid-binding 1,5-diarylpyrazole derivatives.

Li MH, Yin LL, Cai MJ, Zhang WY, Huang Y, Wang X, Zhu XZ, Shen JK. Li MH, et al. Acta Pharmacol Sin. 2005 Jul;26(7):865-72. doi: 10.1111/j.1745-7254.2005.00151.x. Acta Pharmacol Sin. 2005. PMID: 15960895

4

Design, synthesis, and evaluation of Leu*Ala hydroxyethylene-based non-peptide beta-secretase (BACE) inhibitors.

Xiao K, Li X, Li J, Ma L, Hu B, Yu H, Fu Y, Wang R, Ma Z, Qiu B, Li J, Hu D, Wang X, Shen J. Xiao K, et al. Among authors: shen j. Bioorg Med Chem. 2006 Jul 1;14(13):4535-51. doi: 10.1016/j.bmc.2006.02.024. Epub 2006 Feb 28. Bioorg Med Chem. 2006. PMID: 16510290

5

Construction of a small peptide library related to inhibitor OM99-2 and its structure-activity relationship to beta-secretase.

Hu B, Xiong B, Qiu BY, Li X, Yu HP, Xiao K, Wang X, Li J, Shen JK. Hu B, et al. Among authors: shen jk. Acta Pharmacol Sin. 2006 Dec;27(12):1586-93. doi: 10.1111/j.1745-7254.2006.00432.x. Acta Pharmacol Sin. 2006. PMID: 17112413

6

Quinoxalinylurea derivatives as a novel class of JSP-1 inhibitors.

Zhang L, Qiu B, Xiong B, Li X, Li J, Wang X, Li J, Shen J. Zhang L, et al. Among authors: shen j. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2118-22. doi: 10.1016/j.bmcl.2007.01.094. Epub 2007 Feb 2. Bioorg Med Chem Lett. 2007. PMID: 17303416

7

Discovery of Trp-Nle-Tyr-Met as a novel agonist for human formyl peptide receptor-like 1.

Wan HX, Zhou C, Zhang Y, Sun M, Wang X, Yu H, Yang X, Ye RD, Shen JK, Wang MW. Wan HX, et al. Biochem Pharmacol. 2007 Jul 15;74(2):317-26. doi: 10.1016/j.bcp.2007.04.016. Epub 2007 Apr 22. Biochem Pharmacol. 2007. PMID: 17517377

8

Three-component combinatorial synthesis of a substituted 6H-pyrido[2',1':2,3]imidazo- [4,5-c]isoquinolin-5(6H)-one library with cytotoxic activity.

Meng T, Zhang Z, Hu D, Lin L, Ding J, Wang X, Shen J. Meng T, et al. Among authors: shen j. J Comb Chem. 2007 Sep-Oct;9(5):739-41. doi: 10.1021/cc0700593. Epub 2007 Jun 28. J Comb Chem. 2007. PMID: 17602597 No abstract available.

9

Preparation of 6-substituted quinoxaline JSP-1 inhibitors by microwave accelerated nucleophilic substitution.

Zhang L, Qiu B, Li X, Wang X, Li J, Zhang Y, Liu J, Li J, Shen J. Zhang L, et al. Among authors: shen j. Molecules. 2006 Dec 21;11(12):988-99. doi: 10.3390/11120988. Molecules. 2006. PMID: 18007403 Free PMC article.

10

Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action.

Ling Q, Huang Y, Zhou Y, Cai Z, Xiong B, Zhang Y, Ma L, Wang X, Li X, Li J, Shen J. Ling Q, et al. Among authors: shen j. Bioorg Med Chem. 2008 Aug 1;16(15):7399-409. doi: 10.1016/j.bmc.2008.06.014. Epub 2008 Jun 13. Bioorg Med Chem. 2008. PMID: 18579388

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