Saunders K - Search Results

1

Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domain.

Müller MR, Saunders K, Grace C, Jin M, Piche-Nicholas N, Steven J, O'Dwyer R, Wu L, Khetemenee L, Vugmeyster Y, Hickling TP, Tchistiakova L, Olland S, Gill D, Jensen A, Barelle CJ. Müller MR, et al. Among authors: saunders k. MAbs. 2012 Nov-Dec;4(6):673-85. doi: 10.4161/mabs.22242. MAbs. 2012. PMID: 23676205 Free PMC article.

2

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development.

Steven J, Müller MR, Carvalho MF, Ubah OC, Kovaleva M, Donohoe G, Baddeley T, Cornock D, Saunders K, Porter AJ, Barelle CJ. Steven J, et al. Among authors: saunders k. Front Immunol. 2017 Oct 23;8:1361. doi: 10.3389/fimmu.2017.01361. eCollection 2017. Front Immunol. 2017. PMID: 29109729 Free PMC article.

3

Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis.

O'Dwyer R, Kovaleva M, Zhang J, Steven J, Cummins E, Luxenberg D, Darmanin-Sheehan A, Carvalho MF, Whitters M, Saunders K, Barelle CJ. O'Dwyer R, et al. Among authors: saunders k. J Immunol Res. 2018 Oct 17;2018:4089459. doi: 10.1155/2018/4089459. eCollection 2018. J Immunol Res. 2018. PMID: 30417018 Free PMC article.

4

Impact of In Vitro Passive Permeability in a P-gp-transfected LLC-PK1 Model on the Prediction of the Rat and Human Unbound Brain-to-Plasma Concentration Ratio.

Nicolaï J, Chapy H, Gillent E, Saunders K, Ungell AL, Nicolas JM, Chanteux H. Nicolaï J, et al. Among authors: saunders k. Pharm Res. 2020 Aug 27;37(9):175. doi: 10.1007/s11095-020-02867-z. Pharm Res. 2020. PMID: 32856111

5

The Chemical Synthesis of Knob Domain Antibody Fragments.

Macpherson A, Birtley JR, Broadbridge RJ, Brady K, Schulze MED, Tang Y, Joyce C, Saunders K, Bogle G, Horton J, Kelm S, Taylor RD, Franklin RJ, Selby MD, Laabei M, Wonfor T, Hold A, Stanley P, Vadysirisack D, Shi J, van den Elsen J, Lawson ADG. Macpherson A, et al. Among authors: saunders k. ACS Chem Biol. 2021 Sep 17;16(9):1757-1769. doi: 10.1021/acschembio.1c00472. Epub 2021 Aug 18. ACS Chem Biol. 2021. PMID: 34406751 Free article.

6

(-)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes.

Cuypers ML, Chanteux H, Gillent E, Bonnaillie P, Saunders K, Beckers C, Delatour C, Dell'Aiera S, Ungell AL, Nicolaï J. Cuypers ML, et al. Among authors: saunders k. Drug Metab Dispos. 2020 Nov;48(11):1121-1128. doi: 10.1124/dmd.120.000089. Epub 2020 Aug 24. Drug Metab Dispos. 2020. PMID: 32839278

7

Kappa agonist CovX-Bodies.

Roberts LR, Brady K, Brown A, Davey D, Feng L, Huang H, Liu D, Malet L, McMurray G, Phelan A, Saunders K, Bhat A. Roberts LR, et al. Among authors: saunders k. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4173-8. doi: 10.1016/j.bmcl.2012.04.040. Epub 2012 Apr 25. Bioorg Med Chem Lett. 2012. PMID: 22583618

8

Separation and sample pre-treatment in bioanalysis using monolithic phases: A review.

Saunders KC, Ghanem A, Boon Hon W, Hilder EF, Haddad PR. Saunders KC, et al. Anal Chim Acta. 2009 Oct 12;652(1-2):22-31. doi: 10.1016/j.aca.2009.05.043. Epub 2009 Jun 7. Anal Chim Acta. 2009. PMID: 19786168 Review.

9

Evolution of an open-access quantitative bioanalytical mass spectrometry service in a drug discovery environment.

Wright P, Chassaing C, Cussans N, Gibson D, Green C, Gleave M, Jones R, Macrae P, Saunders K. Wright P, et al. Among authors: saunders k. Biomed Chromatogr. 2006 Jun-Jul;20(6-7):585-96. doi: 10.1002/bmc.668. Biomed Chromatogr. 2006. PMID: 16779781

10

A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.

Youdim KA, Saunders KC. Youdim KA, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 May 15;878(17-18):1326-36. doi: 10.1016/j.jchromb.2010.02.013. Epub 2010 Feb 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20207203 Review.

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