Melnick AM - Search Results

1

EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.

Béguelin W, Popovic R, Teater M, Jiang Y, Bunting KL, Rosen M, Shen H, Yang SN, Wang L, Ezponda T, Martinez-Garcia E, Zhang H, Zheng Y, Verma SK, McCabe MT, Ott HM, Van Aller GS, Kruger RG, Liu Y, McHugh CF, Scott DW, Chung YR, Kelleher N, Shaknovich R, Creasy CL, Gascoyne RD, Wong KK, Cerchietti L, Levine RL, Abdel-Wahab O, Licht JD, Elemento O, Melnick AM. Béguelin W, et al. Among authors: melnick am. Cancer Cell. 2013 May 13;23(5):677-92. doi: 10.1016/j.ccr.2013.04.011. Cancer Cell. 2013. PMID: 23680150 Free PMC article.

2

Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.

Licht JD, Shaknovich R, English MA, Melnick A, Li JY, Reddy JC, Dong S, Chen SJ, Zelent A, Waxman S. Licht JD, et al. Oncogene. 1996 Jan 18;12(2):323-36. Oncogene. 1996. PMID: 8570209

3

The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis.

Shaknovich R, Yeyati PL, Ivins S, Melnick A, Lempert C, Waxman S, Zelent A, Licht JD. Shaknovich R, et al. Mol Cell Biol. 1998 Sep;18(9):5533-45. doi: 10.1128/MCB.18.9.5533. Mol Cell Biol. 1998. PMID: 9710637 Free PMC article.

4

Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia.

Melnick A, Licht JD. Melnick A, et al. Blood. 1999 May 15;93(10):3167-215. Blood. 1999. PMID: 10233871 Free article. Review. No abstract available.

5

The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase.

Ball HJ, Melnick A, Shaknovich R, Kohanski RA, Licht JD. Ball HJ, et al. Nucleic Acids Res. 1999 Oct 15;27(20):4106-13. doi: 10.1093/nar/27.20.4106. Nucleic Acids Res. 1999. PMID: 10497277 Free PMC article.

6

A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF.

Hoatlin ME, Zhi Y, Ball H, Silvey K, Melnick A, Stone S, Arai S, Hawe N, Owen G, Zelent A, Licht JD. Hoatlin ME, et al. Blood. 1999 Dec 1;94(11):3737-47. Blood. 1999. PMID: 10572087 Free article.

7

The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein.

Melnick AM, Westendorf JJ, Polinger A, Carlile GW, Arai S, Ball HJ, Lutterbach B, Hiebert SW, Licht JD. Melnick AM, et al. Mol Cell Biol. 2000 Mar;20(6):2075-86. doi: 10.1128/MCB.20.6.2075-2086.2000. Mol Cell Biol. 2000. PMID: 10688654 Free PMC article.

8

AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein.

Melnick A, Carlile GW, McConnell MJ, Polinger A, Hiebert SW, Licht JD. Melnick A, et al. Blood. 2000 Dec 1;96(12):3939-47. Blood. 2000. PMID: 11090081 Free article.

9

Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.

Melnick A, Carlile G, Ahmad KF, Kiang CL, Corcoran C, Bardwell V, Prive GG, Licht JD. Melnick A, et al. Mol Cell Biol. 2002 Mar;22(6):1804-18. doi: 10.1128/MCB.22.6.1804-1818.2002. Mol Cell Biol. 2002. PMID: 11865059 Free PMC article.

10

Histone deacetylases as therapeutic targets in hematologic malignancies.

Melnick A, Licht JD. Melnick A, et al. Curr Opin Hematol. 2002 Jul;9(4):322-32. doi: 10.1097/00062752-200207000-00010. Curr Opin Hematol. 2002. PMID: 12042707 Review.

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