Chaturvedi P - Search Results

1

Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans.

Evans EK, Tester R, Aslanian S, Karp R, Sheets M, Labenski MT, Witowski SR, Lounsbury H, Chaturvedi P, Mazdiyasni H, Zhu Z, Nacht M, Freed MI, Petter RC, Dubrovskiy A, Singh J, Westlin WF. Evans EK, et al. Among authors: chaturvedi p. J Pharmacol Exp Ther. 2013 Aug;346(2):219-28. doi: 10.1124/jpet.113.203489. Epub 2013 May 24. J Pharmacol Exp Ther. 2013. PMID: 23709115 Clinical Trial.

2

Discovery of a potent and isoform-selective targeted covalent inhibitor of the lipid kinase PI3Kα.

Nacht M, Qiao L, Sheets MP, St Martin T, Labenski M, Mazdiyasni H, Karp R, Zhu Z, Chaturvedi P, Bhavsar D, Niu D, Westlin W, Petter RC, Medikonda AP, Singh J. Nacht M, et al. Among authors: chaturvedi p. J Med Chem. 2013 Feb 14;56(3):712-21. doi: 10.1021/jm3008745. Epub 2013 Feb 5. J Med Chem. 2013. PMID: 23360348

3

Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC.

Walter AO, Sjin RT, Haringsma HJ, Ohashi K, Sun J, Lee K, Dubrovskiy A, Labenski M, Zhu Z, Wang Z, Sheets M, St Martin T, Karp R, van Kalken D, Chaturvedi P, Niu D, Nacht M, Petter RC, Westlin W, Lin K, Jaw-Tsai S, Raponi M, Van Dyke T, Etter J, Weaver Z, Pao W, Singh J, Simmons AD, Harding TC, Allen A. Walter AO, et al. Among authors: chaturvedi p. Cancer Discov. 2013 Dec;3(12):1404-15. doi: 10.1158/2159-8290.CD-13-0314. Epub 2013 Sep 24. Cancer Discov. 2013. PMID: 24065731 Free PMC article.

4

In vitro and in vivo characterization of irreversible mutant-selective EGFR inhibitors that are wild-type sparing.

Tjin Tham Sjin R, Lee K, Walter AO, Dubrovskiy A, Sheets M, Martin TS, Labenski MT, Zhu Z, Tester R, Karp R, Medikonda A, Chaturvedi P, Ren Y, Haringsma H, Etter J, Raponi M, Simmons AD, Harding TC, Niu D, Nacht M, Westlin WF, Petter RC, Allen A, Singh J. Tjin Tham Sjin R, et al. Among authors: chaturvedi p. Mol Cancer Ther. 2014 Jun;13(6):1468-79. doi: 10.1158/1535-7163.MCT-13-0966. Epub 2014 Apr 10. Mol Cancer Ther. 2014. PMID: 24723450

5

Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine.

Hagel M, Niu D, St Martin T, Sheets MP, Qiao L, Bernard H, Karp RM, Zhu Z, Labenski MT, Chaturvedi P, Nacht M, Westlin WF, Petter RC, Singh J. Hagel M, et al. Among authors: chaturvedi p. Nat Chem Biol. 2011 Jan;7(1):22-4. doi: 10.1038/nchembio.492. Epub 2010 Nov 28. Nat Chem Biol. 2011. PMID: 21113170

6

Survival of human milk oligosaccharides in the intestine of infants.

Chaturvedi P, Warren CD, Buescher CR, Pickering LK, Newburg DS. Chaturvedi P, et al. Adv Exp Med Biol. 2001;501:315-23. doi: 10.1007/978-1-4615-1371-1_39. Adv Exp Med Biol. 2001. PMID: 11787697

7

Human milk alphal,2-linked fucosylated oligosaccharides decrease risk of diarrhea due to stable toxin of E. coli in breastfed infants.

Newburg DS, Ruiz-Palacios GM, Altaye M, Chaturvedi P, Guerrero ML, Meinzen-Derr JK, Morrow AL. Newburg DS, et al. Among authors: chaturvedi p. Adv Exp Med Biol. 2004;554:457-61. doi: 10.1007/978-1-4757-4242-8_64. Adv Exp Med Biol. 2004. PMID: 15384624 No abstract available.

8

Innate protection conferred by fucosylated oligosaccharides of human milk against diarrhea in breastfed infants.

Newburg DS, Ruiz-Palacios GM, Altaye M, Chaturvedi P, Meinzen-Derr J, Guerrero Mde L, Morrow AL. Newburg DS, et al. Among authors: chaturvedi p. Glycobiology. 2004 Mar;14(3):253-63. doi: 10.1093/glycob/cwh020. Epub 2003 Nov 24. Glycobiology. 2004. PMID: 14638628

9

Milk oligosaccharide profiles by reversed-phase HPLC of their perbenzoylated derivatives.

Chaturvedi P, Warren CD, Ruiz-Palacios GM, Pickering LK, Newburg DS. Chaturvedi P, et al. Anal Biochem. 1997 Aug 15;251(1):89-97. doi: 10.1006/abio.1997.2250. Anal Biochem. 1997. PMID: 9300087

10

Fucosylated human milk oligosaccharides vary between individuals and over the course of lactation.

Chaturvedi P, Warren CD, Altaye M, Morrow AL, Ruiz-Palacios G, Pickering LK, Newburg DS. Chaturvedi P, et al. Glycobiology. 2001 May;11(5):365-72. doi: 10.1093/glycob/11.5.365. Glycobiology. 2001. PMID: 11425797

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