Constantine KL - Search Results

1

Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: observation of extensive dynamics in an enzyme/inhibitor complex.

Kim SH, Constantine KL, Duke GJ, Goldfarb V, Hunt JT, Johnson S, Kish K, Klei HE, McDonnell PA, Metzler WJ, Mueller L, Poss MA, Fairchild CR, Bhide RS. Kim SH, et al. Among authors: constantine kl. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4107-11. doi: 10.1016/j.bmcl.2013.05.052. Epub 2013 May 23. Bioorg Med Chem Lett. 2013. PMID: 23747226

2

NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein.

McDonnell PA, Constantine KL, Goldfarb V, Johnson SR, Sulsky R, Magnin DR, Robl JA, Caulfield TJ, Parker RA, Taylor DS, Adam LP, Metzler WJ, Mueller L, Farmer BT 2nd. McDonnell PA, et al. Among authors: constantine kl. J Med Chem. 2006 Aug 10;49(16):5013-7. doi: 10.1021/jm060360i. J Med Chem. 2006. PMID: 16884313

3

Multiple and single binding modes of fragment-like kinase inhibitors revealed by molecular modeling, residue type-selective protonation, and nuclear overhauser effects.

Constantine KL, Mueller L, Metzler WJ, McDonnell PA, Todderud G, Goldfarb V, Fan Y, Newitt JA, Kiefer SE, Gao M, Tortolani D, Vaccaro W, Tokarski J. Constantine KL, et al. J Med Chem. 2008 Oct 9;51(19):6225-9. doi: 10.1021/jm800747w. Epub 2008 Sep 5. J Med Chem. 2008. PMID: 18771253

4

Protein-ligand NOE matching: a high-throughput method for binding pose evaluation that does not require protein NMR resonance assignments.

Constantine KL, Davis ME, Metzler WJ, Mueller L, Claus BL. Constantine KL, et al. J Am Chem Soc. 2006 Jun 7;128(22):7252-63. doi: 10.1021/ja060356w. J Am Chem Soc. 2006. PMID: 16734479

5

Refined solution structure of human profilin I.

Metzler WJ, Farmer BT 2nd, Constantine KL, Friedrichs MS, Lavoie T, Mueller L. Metzler WJ, et al. Among authors: constantine kl. Protein Sci. 1995 Mar;4(3):450-9. doi: 10.1002/pro.5560040312. Protein Sci. 1995. PMID: 7795529 Free PMC article.

6

Relaxation study of the backbone dynamics of human profilin by two-dimensional 1H-15N NMR.

Constantine KL, Friedrichs MS, Bell AJ, Lavoie TB, Mueller L, Metzler WJ. Constantine KL, et al. FEBS Lett. 1993 Dec 28;336(3):457-61. doi: 10.1016/0014-5793(93)80855-o. FEBS Lett. 1993. PMID: 8282110 Free article.

7

Characterization of NADP+ binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes.

Constantine KL, Mueller L, Goldfarb V, Wittekind M, Metzler WJ, Yanchunas J Jr, Robertson JG, Malley MF, Friedrichs MS, Farmer BT 2nd. Constantine KL, et al. J Mol Biol. 1997 Apr 18;267(5):1223-46. doi: 10.1006/jmbi.1997.0915. J Mol Biol. 1997. PMID: 9150408

8

Production and characterization of an antibody Fv fragment 15N-labeled in the VL domain only.

Goldfarb V, Wittekind M, Jeffrey PD, Mueller L, Constantine KL. Goldfarb V, et al. Among authors: constantine kl. J Mol Biol. 1993 Jul 5;232(1):15-22. doi: 10.1006/jmbi.1993.1366. J Mol Biol. 1993. PMID: 8331656

9

Characterization of the backbone dynamics of an anti-digoxin antibody VL domain by inverse detected 1H-15N NMR: comparisons with X-ray data for the Fab.

Constantine KL, Friedrichs MS, Goldfarb V, Jeffrey PD, Sheriff S, Mueller L. Constantine KL, et al. Proteins. 1993 Mar;15(3):290-311. doi: 10.1002/prot.340150307. Proteins. 1993. PMID: 8456098

10

Structural and functional characterization of CFE88: evidence that a conserved and essential bacterial protein is a methyltransferase.

Constantine KL, Krystek SR, Healy MD, Doyle ML, Siemers NO, Thanassi J, Yan N, Xie D, Goldfarb V, Yanchunas J, Tao L, Dougherty BA, Farmer BT 2nd. Constantine KL, et al. Protein Sci. 2005 Jun;14(6):1472-84. doi: 10.1110/ps.051389605. Protein Sci. 2005. PMID: 15929997 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

35 results

Search Page

Filters