Philipsen L - Search Results

1

Multimolecular analysis of stable immunological synapses reveals sustained recruitment and sequential assembly of signaling clusters.

Philipsen L, Engels T, Schilling K, Gurbiel S, Fischer KD, Tedford K, Schraven B, Gunzer M, Reichardt P. Philipsen L, et al. Mol Cell Proteomics. 2013 Sep;12(9):2551-67. doi: 10.1074/mcp.M112.025205. Epub 2013 Jun 10. Mol Cell Proteomics. 2013. PMID: 23754785 Free PMC article.

2

Analysis of TCR activation kinetics in primary human T cells upon focal or soluble stimulation.

Arndt B, Poltorak M, Kowtharapu BS, Reichardt P, Philipsen L, Lindquist JA, Schraven B, Simeoni L. Arndt B, et al. Among authors: philipsen l. J Immunol Methods. 2013 Jan 31;387(1-2):276-83. doi: 10.1016/j.jim.2012.11.006. Epub 2012 Nov 22. J Immunol Methods. 2013. PMID: 23178863

3

T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.

Stirnweiss A, Hartig R, Gieseler S, Lindquist JA, Reichardt P, Philipsen L, Simeoni L, Poltorak M, Merten C, Zuschratter W, Prokazov Y, Paster W, Stockinger H, Harder T, Gunzer M, Schraven B. Stirnweiss A, et al. Among authors: philipsen l. Sci Signal. 2013 Feb 19;6(263):ra13. doi: 10.1126/scisignal.2003607. Sci Signal. 2013. PMID: 23423439

4

Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation.

Harder T, Guttek K, Philipsen L, Simeoni L, Schraven B, Reinhold D. Harder T, et al. Among authors: philipsen l. Cell Commun Signal. 2014 Dec 8;12:74. doi: 10.1186/s12964-014-0074-6. Cell Commun Signal. 2014. PMID: 25482031 Free PMC article.

5

D120 and K152 within the PH Domain of T Cell Adapter SKAP55 Regulate Plasma Membrane Targeting of SKAP55 and LFA-1 Affinity Modulation in Human T Lymphocytes.

Witte A, Meineke B, Sticht J, Philipsen L, Kuropka B, Müller AJ, Freund C, Schraven B, Kliche S. Witte A, et al. Among authors: philipsen l. Mol Cell Biol. 2017 Mar 17;37(7):e00509-16. doi: 10.1128/MCB.00509-16. Print 2017 Apr 1. Mol Cell Biol. 2017. PMID: 28052935 Free PMC article.

6

De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling.

Philipsen L, Reddycherla AV, Hartig R, Gumz J, Kästle M, Kritikos A, Poltorak MP, Prokazov Y, Turbin E, Weber A, Zuschratter W, Schraven B, Simeoni L, Müller AJ. Philipsen L, et al. Sci Signal. 2017 Jan 17;10(462):eaaf4736. doi: 10.1126/scisignal.aaf4736. Sci Signal. 2017. PMID: 28096507

7

Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1.

Bernhardt A, Fehr A, Brandt S, Jerchel S, Ballhause TM, Philipsen L, Stolze S, Geffers R, Weng H, Fischer KD, Isermann B, Brunner-Weinzierl MC, Batra A, Siegmund B, Zhu C, Lindquist JA, Mertens PR. Bernhardt A, et al. Among authors: philipsen l. Kidney Int. 2017 Nov;92(5):1157-1177. doi: 10.1016/j.kint.2017.03.035. Epub 2017 Jun 11. Kidney Int. 2017. PMID: 28610763 Free article.

8

TCR signalling network organization at the immunological synapses of murine regulatory T cells.

van Ham M, Teich R, Philipsen L, Niemz J, Amsberg N, Wissing J, Nimtz M, Gröbe L, Kliche S, Thiel N, Klawonn F, Hubo M, Jonuleit H, Reichardt P, Müller AJ, Huehn J, Jänsch L. van Ham M, et al. Among authors: philipsen l. Eur J Immunol. 2017 Dec;47(12):2043-2058. doi: 10.1002/eji.201747041. Epub 2017 Sep 12. Eur J Immunol. 2017. PMID: 28833060 Free article.

9

JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.

Edelmann B, Gupta N, Schnoeder TM, Oelschlegel AM, Shahzad K, Goldschmidt J, Philipsen L, Weinert S, Ghosh A, Saalfeld FC, Nimmagadda SC, Müller P, Braun-Dullaeus R, Mohr J, Wolleschak D, Kliche S, Amthauer H, Heidel FH, Schraven B, Isermann B, Müller AJ, Fischer T. Edelmann B, et al. Among authors: philipsen l. J Clin Invest. 2018 Oct 1;128(10):4359-4371. doi: 10.1172/JCI90312. Epub 2018 Jul 19. J Clin Invest. 2018. PMID: 30024857 Free PMC article.

10

CD11c-expressing Ly6C+CCR2+ monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission.

Heyde S, Philipsen L, Formaglio P, Fu Y, Baars I, Höbbel G, Kleinholz CL, Seiß EA, Stettin J, Gintschel P, Dudeck A, Bousso P, Schraven B, Müller AJ. Heyde S, et al. Among authors: philipsen l. PLoS Pathog. 2018 Oct 22;14(10):e1007374. doi: 10.1371/journal.ppat.1007374. eCollection 2018 Oct. PLoS Pathog. 2018. PMID: 30346994 Free PMC article.

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