Frank A - Search Results

1

Engineering an enantioselective amine oxidase for the synthesis of pharmaceutical building blocks and alkaloid natural products.

Ghislieri D, Green AP, Pontini M, Willies SC, Rowles I, Frank A, Grogan G, Turner NJ. Ghislieri D, et al. Among authors: frank a. J Am Chem Soc. 2013 Jul 24;135(29):10863-9. doi: 10.1021/ja4051235. Epub 2013 Jul 15. J Am Chem Soc. 2013. PMID: 23808566

2

Structure and activity of NADPH-dependent reductase Q1EQE0 from Streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate.

Rodríguez-Mata M, Frank A, Wells E, Leipold F, Turner NJ, Hart S, Turkenburg JP, Grogan G. Rodríguez-Mata M, et al. Among authors: frank a. Chembiochem. 2013 Jul 22;14(11):1372-9. doi: 10.1002/cbic.201300321. Epub 2013 Jun 28. Chembiochem. 2013. PMID: 23813853

3

Structures of the Apo and FAD-bound forms of 2-hydroxybiphenyl 3-monooxygenase (HbpA) locate activity hotspots identified by using directed evolution.

Jensen CN, Mielke T, Farrugia JE, Frank A, Man H, Hart S, Turkenburg JP, Grogan G. Jensen CN, et al. Among authors: frank a. Chembiochem. 2015 Apr 13;16(6):968-76. doi: 10.1002/cbic.201402701. Epub 2015 Mar 3. Chembiochem. 2015. PMID: 25737306 Free PMC article.

4

Tolerance of β-diketone hydrolases as representatives of the crotonase superfamily towards organic solvents.

Siirola E, Grischek B, Clay D, Frank A, Grogan G, Kroutil W. Siirola E, et al. Among authors: frank a. Biotechnol Bioeng. 2011 Dec;108(12):2815-22. doi: 10.1002/bit.23275. Epub 2011 Aug 4. Biotechnol Bioeng. 2011. PMID: 21809324

5

Perceptions of key informant neurologists before implementing anti-amyloid drugs in the Spanish departments of neurology.

Matias-Guiu JA, Álvarez-Sabín J, Botia E, Casado-Naranjo I, Castellanos M, Frank A, Íñiguez C, Jiménez-Hernández MD, Jiménez-Jiménez FJ, Láinez JM, Moral E, Pérez-Martínez DA, Rodríguez-Antigüedad A, Ruiz-Lavilla N, Segura T, Serrano-Castro PJ, Matias-Guiu J. Matias-Guiu JA, et al. Among authors: frank a. J Alzheimers Dis. 2024 Nov;102(1):207-217. doi: 10.1177/13872877241284312. J Alzheimers Dis. 2024. PMID: 39497319

6

SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma.

Daley BR, Sealover NE, Finniff BA, Hughes JM, Sheffels E, Gerlach D, Hofmann MH, Kostyrko K, LaMorte JP, Linke A, Beckley Z, Frank AM, Lewis RE, Wilkerson MD, Dalgard C, Kortum RL. Daley BR, et al. Among authors: frank am. Cancer Res. 2024 Oct 22. doi: 10.1158/0008-5472.CAN-23-3256. Online ahead of print. Cancer Res. 2024. PMID: 39437166

7

Development and Initial Testing of an Artificial Intelligence-Based Virtual Reality Companion for People Living with Dementia in Long-Term Care.

Sheehy L, Bouchard S, Kakkar A, El Hakim R, Lhoest J, Frank A. Sheehy L, et al. Among authors: frank a. J Clin Med. 2024 Sep 20;13(18):5574. doi: 10.3390/jcm13185574. J Clin Med. 2024. PMID: 39337060 Free PMC article.

8

Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness.

Barkan DT, Garland K, Zhang L, Eastman RT, Hesse M, Knapp M, Ornelas E, Tang J, Cortopassi WA, Wang Y, King F, Jia W, Nguyen Z, Frank AO, Chan R, Fang E, Fuller D, Busby S, Carias H, Donahue K, Tandeske L, Diagana TT, Jarrousse N, Moser H, Sarko C, Dovala D, Moquin S, Marx VM. Barkan DT, et al. Among authors: frank ao. J Med Chem. 2024 Oct 10;67(19):17454-17471. doi: 10.1021/acs.jmedchem.4c01404. Epub 2024 Sep 27. J Med Chem. 2024. PMID: 39332817 Free PMC article.

9

Histamine H₃ receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection.

Sgambellone S, Khanfar MA, Marri S, Villano S, Nardini P, Frank A, Reiner-Link D, Stark H, Lucarini L. Sgambellone S, et al. Among authors: frank a. Biomed Pharmacother. 2024 Nov;180:117454. doi: 10.1016/j.biopha.2024.117454. Epub 2024 Sep 24. Biomed Pharmacother. 2024. PMID: 39321511 Free article.

10

N1-Methylpseudouridine and pseudouridine modifications modulate mRNA decoding during translation.

Monroe J, Eyler DE, Mitchell L, Deb I, Bojanowski A, Srinivas P, Dunham CM, Roy B, Frank AT, Koutmou KS. Monroe J, et al. Among authors: frank at. Nat Commun. 2024 Sep 16;15(1):8119. doi: 10.1038/s41467-024-51301-0. Nat Commun. 2024. PMID: 39284850 Free PMC article.

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