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Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143.
Blumensatt M, Greulich S, Herzfeld de Wiza D, Mueller H, Maxhera B, Rabelink MJ, Hoeben RC, Akhyari P, Al-Hasani H, Ruige JB, Ouwens DM. Blumensatt M, et al. Among authors: ruige jb. Cardiovasc Res. 2013 Nov 1;100(2):201-10. doi: 10.1093/cvr/cvt173. Epub 2013 Jun 28. Cardiovasc Res. 2013. PMID: 23812417
Activin A is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes.
Chen WJ, Greulich S, van der Meer RW, Rijzewijk LJ, Lamb HJ, de Roos A, Smit JW, Romijn JA, Ruige JB, Lammertsma AA, Lubberink M, Diamant M, Ouwens DM. Chen WJ, et al. Among authors: ruige jb. Cardiovasc Diabetol. 2013 Oct 17;12:150. doi: 10.1186/1475-2840-12-150. Cardiovasc Diabetol. 2013. PMID: 24134550 Free PMC article. Clinical Trial.
Secretory products from epicardial adipose tissue from patients with type 2 diabetes impair mitochondrial β-oxidation in cardiomyocytes via activation of the cardiac renin-angiotensin system and induction of miR-208a.
Blumensatt M, Fahlbusch P, Hilgers R, Bekaert M, Herzfeld de Wiza D, Akhyari P, Ruige JB, Ouwens DM. Blumensatt M, et al. Among authors: ruige jb. Basic Res Cardiol. 2017 Jan;112(1):2. doi: 10.1007/s00395-016-0591-0. Epub 2016 Nov 18. Basic Res Cardiol. 2017. PMID: 27864612
Sex steroid-induced changes in circulating monocyte chemoattractant protein-1 levels may contribute to metabolic dysfunction in obese men.
Ruige JB, Bekaert M, Lapauw B, Fiers T, Lehr S, Hartwig S, Herzfeld de Wiza D, Schiller M, Passlack W, Van Nieuwenhove Y, Pattyn P, Cuvelier C, Taes YE, Sell H, Eckel J, Kaufman JM, Ouwens DM. Ruige JB, et al. J Clin Endocrinol Metab. 2012 Jul;97(7):E1187-91. doi: 10.1210/jc.2011-3069. Epub 2012 Apr 20. J Clin Endocrinol Metab. 2012. PMID: 22523336
62 results