Dodson CA - Search Results

1

A kinetic test characterizes kinase intramolecular and intermolecular autophosphorylation mechanisms.

Dodson CA, Yeoh S, Haq T, Bayliss R. Dodson CA, et al. Sci Signal. 2013 Jul 2;6(282):ra54. doi: 10.1126/scisignal.2003910. Sci Signal. 2013. PMID: 23821772

2

Activation of Aurora-A kinase by protein partner binding and phosphorylation are independent and synergistic.

Dodson CA, Bayliss R. Dodson CA, et al. J Biol Chem. 2012 Jan 6;287(2):1150-7. doi: 10.1074/jbc.M111.312090. Epub 2011 Nov 16. J Biol Chem. 2012. PMID: 22094468 Free PMC article.

3

The structural mechanisms that underpin mitotic kinase activation.

Dodson CA, Haq T, Yeoh S, Fry AM, Bayliss R. Dodson CA, et al. Biochem Soc Trans. 2013 Aug;41(4):1037-41. doi: 10.1042/BST20130066. Biochem Soc Trans. 2013. PMID: 23863175 Review.

4

Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design.

Dodson CA, Kosmopoulou M, Richards MW, Atrash B, Bavetsias V, Blagg J, Bayliss R. Dodson CA, et al. Biochem J. 2010 Mar 15;427(1):19-28. doi: 10.1042/BJ20091530. Biochem J. 2010. PMID: 20067443

5

Dynamic Equilibrium of the Aurora A Kinase Activation Loop Revealed by Single-Molecule Spectroscopy.

Gilburt JAH, Sarkar H, Sheldrake P, Blagg J, Ying L, Dodson CA. Gilburt JAH, et al. Among authors: dodson ca. Angew Chem Int Ed Engl. 2017 Sep 11;56(38):11409-11414. doi: 10.1002/anie.201704654. Epub 2017 Aug 7. Angew Chem Int Ed Engl. 2017. PMID: 28700101 Free PMC article.

6

Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation.

Gilburt JAH, Girvan P, Blagg J, Ying L, Dodson CA. Gilburt JAH, et al. Among authors: dodson ca. Chem Sci. 2019 Mar 4;10(14):4069-4076. doi: 10.1039/c8sc03669a. eCollection 2019 Apr 14. Chem Sci. 2019. PMID: 31015948 Free PMC article.

7

Production of Protein Kinases in E. coli.

Dodson CA. Dodson CA. Methods Mol Biol. 2017;1586:251-264. doi: 10.1007/978-1-4939-6887-9_16. Methods Mol Biol. 2017. PMID: 28470610

8

Kinetic Analysis Reveals the Identity of Aβ-Metal Complex Responsible for the Initial Aggregation of Aβ in the Synapse.

Branch T, Barahona M, Dodson CA, Ying L. Branch T, et al. Among authors: dodson ca. ACS Chem Neurosci. 2017 Sep 20;8(9):1970-1979. doi: 10.1021/acschemneuro.7b00121. Epub 2017 Jun 29. ACS Chem Neurosci. 2017. PMID: 28621929 Free PMC article.

9

A simple, robust, universal assay for real-time enzyme monitoring by signalling changes in nucleoside phosphate anion concentration using a europium(iii)-based anion receptor.

Hewitt SH, Ali R, Mailhot R, Antonen CR, Dodson CA, Butler SJ. Hewitt SH, et al. Among authors: dodson ca. Chem Sci. 2019 May 1;10(20):5373-5381. doi: 10.1039/c9sc01552c. eCollection 2019 May 28. Chem Sci. 2019. PMID: 31191895 Free PMC article.

10

A radical sense of direction: signalling and mechanism in cryptochrome magnetoreception.

Dodson CA, Hore PJ, Wallace MI. Dodson CA, et al. Trends Biochem Sci. 2013 Sep;38(9):435-46. doi: 10.1016/j.tibs.2013.07.002. Epub 2013 Aug 9. Trends Biochem Sci. 2013. PMID: 23938034 Review.

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