García-Sastre A - Search Results

1

Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.

Tsai PL, Chiou NT, Kuss S, García-Sastre A, Lynch KW, Fontoura BM. Tsai PL, et al. PLoS Pathog. 2013;9(6):e1003460. doi: 10.1371/journal.ppat.1003460. Epub 2013 Jun 27. PLoS Pathog. 2013. PMID: 23825951 Free PMC article.

2

Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines.

Manicassamy B, Medina RA, Hai R, Tsibane T, Stertz S, Nistal-Villán E, Palese P, Basler CF, García-Sastre A. Manicassamy B, et al. PLoS Pathog. 2010 Jan 29;6(1):e1000745. doi: 10.1371/journal.ppat.1000745. PLoS Pathog. 2010. PMID: 20126449 Free PMC article.

3

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein.

Varga ZT, Ramos I, Hai R, Schmolke M, García-Sastre A, Fernandez-Sesma A, Palese P. Varga ZT, et al. PLoS Pathog. 2011 Jun;7(6):e1002067. doi: 10.1371/journal.ppat.1002067. Epub 2011 Jun 9. PLoS Pathog. 2011. PMID: 21695240 Free PMC article.

4

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species.

Schmolke M, Manicassamy B, Pena L, Sutton T, Hai R, Varga ZT, Hale BG, Steel J, Pérez DR, García-Sastre A. Schmolke M, et al. PLoS Pathog. 2011 Aug;7(8):e1002186. doi: 10.1371/journal.ppat.1002186. Epub 2011 Aug 11. PLoS Pathog. 2011. PMID: 21852950 Free PMC article.

5

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.

Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM. Mata MA, et al. Nat Chem Biol. 2011 Sep 11;7(10):712-9. doi: 10.1038/nchembio.645. Nat Chem Biol. 2011. PMID: 21909097 Free PMC article.

6

Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.

Zhang L, Das P, Schmolke M, Manicassamy B, Wang Y, Deng X, Cai L, Tu BP, Forst CV, Roth MG, Levy DE, García-Sastre A, de Brabander J, Phillips MA, Fontoura BM. Zhang L, et al. J Cell Biol. 2012 Feb 6;196(3):315-26. doi: 10.1083/jcb.201107058. J Cell Biol. 2012. PMID: 22312003 Free PMC article.

7

Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction.

Noronha JM, Liu M, Squires RB, Pickett BE, Hale BG, Air GM, Galloway SE, Takimoto T, Schmolke M, Hunt V, Klem E, García-Sastre A, McGee M, Scheuermann RH. Noronha JM, et al. J Virol. 2012 May;86(10):5857-66. doi: 10.1128/JVI.06901-11. Epub 2012 Mar 7. J Virol. 2012. PMID: 22398283 Free PMC article.

8

Host modulators of H1N1 cytopathogenicity.

Ward SE, Kim HS, Komurov K, Mendiratta S, Tsai PL, Schmolke M, Satterly N, Manicassamy B, Forst CV, Roth MG, García-Sastre A, Blazewska KM, McKenna CE, Fontoura BM, White MA. Ward SE, et al. PLoS One. 2012;7(8):e39284. doi: 10.1371/journal.pone.0039284. Epub 2012 Aug 2. PLoS One. 2012. PMID: 22876275 Free PMC article.

9

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU. Rajsbaum R, et al. PLoS Pathog. 2012;8(11):e1003059. doi: 10.1371/journal.ppat.1003059. Epub 2012 Nov 29. PLoS Pathog. 2012. PMID: 23209422 Free PMC article.

10

Influenza virus mRNA trafficking through host nuclear speckles.

Mor A, White A, Zhang K, Thompson M, Esparza M, Muñoz-Moreno R, Koide K, Lynch KW, García-Sastre A, Fontoura BM. Mor A, et al. Nat Microbiol. 2016 May 27;1(7):16069. doi: 10.1038/nmicrobiol.2016.69. Nat Microbiol. 2016. PMID: 27572970 Free PMC article.

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