Aiuti A - Search Results

1

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC, Bosticardo M, Evangelio C, Assanelli A, Casiraghi M, Di Nunzio S, Callegaro L, Benati C, Rizzardi P, Pellin D, Di Serio C, Schmidt M, Von Kalle C, Gardner J, Mehta N, Neduva V, Dow DJ, Galy A, Miniero R, Finocchi A, Metin A, Banerjee PP, Orange JS, Galimberti S, Valsecchi MG, Biffi A, Montini E, Villa A, Ciceri F, Roncarolo MG, Naldini L. Aiuti A, et al. Science. 2013 Aug 23;341(6148):1233151. doi: 10.1126/science.1233151. Epub 2013 Jul 11. Science. 2013. PMID: 23845947 Free PMC article. Clinical Trial.

2

A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors.

Dando JS, Roncarolo MG, Bordignon C, Aiuti A. Dando JS, et al. Among authors: aiuti a. Hum Gene Ther. 2001 Nov 1;12(16):1979-88. doi: 10.1089/104303401753204553. Hum Gene Ther. 2001. PMID: 11686939

3

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning.

Aiuti A, Slavin S, Aker M, Ficara F, Deola S, Mortellaro A, Morecki S, Andolfi G, Tabucchi A, Carlucci F, Marinello E, Cattaneo F, Vai S, Servida P, Miniero R, Roncarolo MG, Bordignon C. Aiuti A, et al. Science. 2002 Jun 28;296(5577):2410-3. doi: 10.1126/science.1070104. Science. 2002. PMID: 12089448 Clinical Trial.

4

Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation.

Dupré L, Aiuti A, Trifari S, Martino S, Saracco P, Bordignon C, Roncarolo MG. Dupré L, et al. Among authors: aiuti a. Immunity. 2002 Aug;17(2):157-66. doi: 10.1016/s1074-7613(02)00360-6. Immunity. 2002. PMID: 12196287 Free article.

5

Gene therapy for adenosine deaminase deficiency.

Aiuti A, Ficara F, Cattaneo F, Bordignon C, Roncarolo MG. Aiuti A, et al. Curr Opin Allergy Clin Immunol. 2003 Dec;3(6):461-6. doi: 10.1097/00130832-200312000-00007. Curr Opin Allergy Clin Immunol. 2003. PMID: 14612670 Review.

6

Mobilized blood CD34+ cells transduced and selected with a clinically applicable protocol reconstitute lymphopoiesis in SCID-Hu mice.

Deola S, Scaramuzza S, Birolo RS, Carballido-Perrig N, Ficara F, Mocchetti C, Dando J, Carballido JM, Bordignon C, Roncarolo MG, Bregni M, Aiuti A. Deola S, et al. Among authors: aiuti a. Hum Gene Ther. 2004 Mar;15(3):305-11. doi: 10.1089/104303404322886156. Hum Gene Ther. 2004. PMID: 15018739

7

Efficient gene transfer into primitive hematopoietic progenitors using a bone marrow microenvironment cell line engineered to produce retroviral vectors.

Dando JS, Ficara F, Deola S, Roncarolo MG, Bordignon C, Aiuti A. Dando JS, et al. Among authors: aiuti a. Haematologica. 2004 Apr;89(4):462-70. Haematologica. 2004. PMID: 15075080

8

Gene therapy for adenosine-deaminase-deficient severe combined immunodeficiency.

Aiuti A. Aiuti A. Best Pract Res Clin Haematol. 2004 Sep;17(3):505-16. doi: 10.1016/j.beha.2004.05.012. Best Pract Res Clin Haematol. 2004. PMID: 15498720 Review.

9

Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction.

Dupré L, Trifari S, Follenzi A, Marangoni F, Lain de Lera T, Bernad A, Martino S, Tsuchiya S, Bordignon C, Naldini L, Aiuti A, Roncarolo MG. Dupré L, et al. Among authors: aiuti a. Mol Ther. 2004 Nov;10(5):903-15. doi: 10.1016/j.ymthe.2004.08.008. Mol Ther. 2004. PMID: 15509508 Free article.

10

IL-3 or IL-7 increases ex vivo gene transfer efficiency in ADA-SCID BM CD34+ cells while maintaining in vivo lymphoid potential.

Ficara F, Superchi DB, Hernández RJ, Mocchetti C, Carballido-Perrig N, Andolfi G, Deola S, Colombo A, Bordignon C, Carballido JM, Roncarolo MG, Aiuti A. Ficara F, et al. Among authors: aiuti a. Mol Ther. 2004 Dec;10(6):1096-108. doi: 10.1016/j.ymthe.2004.08.014. Mol Ther. 2004. PMID: 15564141 Free article.

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