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Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G>A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients.
Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A. Hitomi T, et al. Among authors: kobayashi h. Biochem Biophys Res Commun. 2013 Aug 16;438(1):13-9. doi: 10.1016/j.bbrc.2013.07.004. Epub 2013 Jul 12. Biochem Biophys Res Commun. 2013. PMID: 23850618
A rare Asian founder polymorphism of Raptor may explain the high prevalence of Moyamoya disease among East Asians and its low prevalence among Caucasians.
Liu W, Hashikata H, Inoue K, Matsuura N, Mineharu Y, Kobayashi H, Kikuta K, Takagi Y, Hitomi T, Krischek B, Zou LP, Fang F, Herzig R, Kim JE, Kang HS, Oh CW, Tregouet DA, Hashimoto N, Koizumi A. Liu W, et al. Among authors: kobayashi h. Environ Health Prev Med. 2010 Mar;15(2):94-104. doi: 10.1007/s12199-009-0116-7. Epub 2009 Nov 19. Environ Health Prev Med. 2010. PMID: 19921495 Free PMC article.
Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development.
Liu W, Morito D, Takashima S, Mineharu Y, Kobayashi H, Hitomi T, Hashikata H, Matsuura N, Yamazaki S, Toyoda A, Kikuta K, Takagi Y, Harada KH, Fujiyama A, Herzig R, Krischek B, Zou L, Kim JE, Kitakaze M, Miyamoto S, Nagata K, Hashimoto N, Koizumi A. Liu W, et al. Among authors: kobayashi h. PLoS One. 2011;6(7):e22542. doi: 10.1371/journal.pone.0022542. Epub 2011 Jul 20. PLoS One. 2011. PMID: 21799892 Free PMC article.
Preliminary assessment of ecological exposure of adult residents in Fukushima Prefecture to radioactive cesium through ingestion and inhalation.
Koizumi A, Harada KH, Niisoe T, Adachi A, Fujii Y, Hitomi T, Kobayashi H, Wada Y, Watanabe T, Ishikawa H. Koizumi A, et al. Among authors: kobayashi h. Environ Health Prev Med. 2012 Jul;17(4):292-8. doi: 10.1007/s12199-011-0251-9. Epub 2011 Nov 10. Environ Health Prev Med. 2012. PMID: 22071665 Free PMC article.
[Genes associated with moyamoya syndrome and disease].
Koizumi A, Kobayashi H, Hitomi T. Koizumi A, et al. Among authors: kobayashi h. No Shinkei Geka. 2012 Feb;40(2):105-18. No Shinkei Geka. 2012. PMID: 22281463 Review. Japanese. No abstract available.
P.R4810K, a polymorphism of RNF213, the susceptibility gene for moyamoya disease, is associated with blood pressure.
Koizumi A, Kobayashi H, Liu W, Fujii Y, Senevirathna ST, Nanayakkara S, Okuda H, Hitomi T, Harada KH, Takenaka K, Watanabe T, Shimbo S. Koizumi A, et al. Among authors: kobayashi h. Environ Health Prev Med. 2013 Mar;18(2):121-9. doi: 10.1007/s12199-012-0299-1. Epub 2012 Aug 10. Environ Health Prev Med. 2013. PMID: 22878964 Free PMC article.
Ablation of Rnf213 retards progression of diabetes in the Akita mouse.
Kobayashi H, Yamazaki S, Takashima S, Liu W, Okuda H, Yan J, Fujii Y, Hitomi T, Harada KH, Habu T, Koizumi A. Kobayashi H, et al. Biochem Biophys Res Commun. 2013 Mar 15;432(3):519-25. doi: 10.1016/j.bbrc.2013.02.015. Epub 2013 Feb 11. Biochem Biophys Res Commun. 2013. PMID: 23410753
9,504 results