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Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G>A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients.
Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A. Hitomi T, et al. Among authors: osafune k. Biochem Biophys Res Commun. 2013 Aug 16;438(1):13-9. doi: 10.1016/j.bbrc.2013.07.004. Epub 2013 Jul 12. Biochem Biophys Res Commun. 2013. PMID: 23850618
Genetically matched human iPS cells reveal that propensity for cartilage and bone differentiation differs with clones, not cell type of origin.
Nasu A, Ikeya M, Yamamoto T, Watanabe A, Jin Y, Matsumoto Y, Hayakawa K, Amano N, Sato S, Osafune K, Aoyama T, Nakamura T, Kato T, Toguchida J. Nasu A, et al. Among authors: osafune k. PLoS One. 2013;8(1):e53771. doi: 10.1371/journal.pone.0053771. Epub 2013 Jan 31. PLoS One. 2013. PMID: 23382851 Free PMC article.
The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431) induces genomic instability by mitotic abnormality.
Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A. Hitomi T, et al. Among authors: osafune k. Biochem Biophys Res Commun. 2013 Oct 4;439(4):419-26. doi: 10.1016/j.bbrc.2013.08.067. Epub 2013 Aug 27. Biochem Biophys Res Commun. 2013. PMID: 23994138
Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency.
Yasuno T, Osafune K, Sakurai H, Asaka I, Tanaka A, Yamaguchi S, Yamada K, Hitomi H, Arai S, Kurose Y, Higaki Y, Sudo M, Ando S, Nakashima H, Saito T, Kaneoka H. Yasuno T, et al. Among authors: osafune k. Biochem Biophys Res Commun. 2014 May 30;448(2):175-81. doi: 10.1016/j.bbrc.2014.04.084. Epub 2014 Apr 26. Biochem Biophys Res Commun. 2014. PMID: 24780397
Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice.
Toyohara T, Mae S, Sueta S, Inoue T, Yamagishi Y, Kawamoto T, Kasahara T, Hoshina A, Toyoda T, Tanaka H, Araoka T, Sato-Otsubo A, Takahashi K, Sato Y, Yamaji N, Ogawa S, Yamanaka S, Osafune K. Toyohara T, et al. Among authors: osafune k. Stem Cells Transl Med. 2015 Sep;4(9):980-92. doi: 10.5966/sctm.2014-0219. Epub 2015 Jul 21. Stem Cells Transl Med. 2015. PMID: 26198166 Free PMC article.
93 results