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Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G>A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients.
Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A. Hitomi T, et al. Among authors: takagi y. Biochem Biophys Res Commun. 2013 Aug 16;438(1):13-9. doi: 10.1016/j.bbrc.2013.07.004. Epub 2013 Jul 12. Biochem Biophys Res Commun. 2013. PMID: 23850618
[Current knowledge on the genetic factors involved in moyamoya disease].
Hashikata H, Liu W, Mineharu Y, Inoue K, Takenaka K, Ikeda H, Houkin K, Kuroda S, Kikuchi K, Kimura M, Taki T, Sonobe M, Ban S, Nogaki H, Handa A, Kikuta K, Takagi Y, Nozaki K, Hashimoto N, Koizumi A. Hashikata H, et al. Among authors: takagi y. Brain Nerve. 2008 Nov;60(11):1261-9. Brain Nerve. 2008. PMID: 19069159 Review. Japanese.
A rare Asian founder polymorphism of Raptor may explain the high prevalence of Moyamoya disease among East Asians and its low prevalence among Caucasians.
Liu W, Hashikata H, Inoue K, Matsuura N, Mineharu Y, Kobayashi H, Kikuta K, Takagi Y, Hitomi T, Krischek B, Zou LP, Fang F, Herzig R, Kim JE, Kang HS, Oh CW, Tregouet DA, Hashimoto N, Koizumi A. Liu W, et al. Among authors: takagi y. Environ Health Prev Med. 2010 Mar;15(2):94-104. doi: 10.1007/s12199-009-0116-7. Epub 2009 Nov 19. Environ Health Prev Med. 2010. PMID: 19921495 Free PMC article.
2,310 results