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ISSLS prize winner: disc dynamic compression in rats produces long-lasting increases in inflammatory mediators in discs and induces long-lasting nerve injury and regeneration of the afferent fibers innervating discs: a pathomechanism for chronic discogenic low back pain.
Miyagi M, Ishikawa T, Kamoda H, Suzuki M, Murakami K, Shibayama M, Orita S, Eguchi Y, Arai G, Sakuma Y, Kubota G, Oikawa Y, Ozawa T, Aoki Y, Toyone T, Takahashi K, Inoue G, Kawakami M, Ohtori S. Miyagi M, et al. Among authors: ishikawa t. Spine (Phila Pa 1976). 2012 Oct 1;37(21):1810-8. doi: 10.1097/BRS.0b013e31824ffac6. Spine (Phila Pa 1976). 2012. PMID: 22366969
Disk injury in rats produces persistent increases in pain-related neuropeptides in dorsal root ganglia and spinal cord glia but only transient increases in inflammatory mediators: pathomechanism of chronic diskogenic low back pain.
Miyagi M, Ishikawa T, Orita S, Eguchi Y, Kamoda H, Arai G, Suzuki M, Inoue G, Aoki Y, Toyone T, Takahashi K, Ohtori S. Miyagi M, et al. Among authors: ishikawa t. Spine (Phila Pa 1976). 2011 Dec 15;36(26):2260-6. doi: 10.1097/BRS.0b013e31820e68c7. Spine (Phila Pa 1976). 2011. PMID: 21228748
Muscle injury in rats induces upregulation of inflammatory cytokines in injured muscle and calcitonin gene-related peptide in dorsal root ganglia innervating the injured muscle.
Sakuma Y, Miyagi M, Inoue G, Ishikawa T, Kamoda H, Yamauchi K, Orita S, Suzuki M, Oikawa Y, Inage K, Kubota G, Sainoh T, Sato J, Takahashi K, Ohtori S. Sakuma Y, et al. Among authors: ishikawa t. Muscle Nerve. 2016 Oct;54(4):776-82. doi: 10.1002/mus.25092. Epub 2016 Jul 14. Muscle Nerve. 2016. PMID: 26930007 Free PMC article.
Direct single injection of p38 mitogen-activated protein kinase inhibitor does not affect calcitonin gene-related peptide expression in dorsal root ganglion neurons innervating punctured discs in rats.
Hayashi Y, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Fukui Y, Wakai K, Kuniyoshi K, Ishikawa T, Arai G, Miyagi M, Kamoda H, Aoki Y, Takahashi K. Hayashi Y, et al. Among authors: ishikawa t. Spine (Phila Pa 1976). 2009 Dec 15;34(26):2843-7. doi: 10.1097/BRS.0b013e3181b8db15. Spine (Phila Pa 1976). 2009. PMID: 20010392
Inhibiting nerve growth factor or its receptors downregulates calcitonin gene-related peptide expression in rat lumbar dorsal root ganglia innervating injured intervertebral discs.
Orita S, Ohtori S, Nagata M, Horii M, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Eguchi Y, Kamoda H, Arai G, Ishikawa T, Miyagi M, Ochiai N, Kishida S, Takaso M, Aoki Y, Takahashi K. Orita S, et al. Among authors: ishikawa t. J Orthop Res. 2010 Dec;28(12):1614-20. doi: 10.1002/jor.21170. J Orthop Res. 2010. PMID: 20973063 Free article.
7,803 results