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Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes.
Cheng Q, Law PK, de Gasparo M, Leung PS. Cheng Q, et al. Among authors: leung ps. J Pharmacol Exp Ther. 2008 Dec;327(3):683-91. doi: 10.1124/jpet.108.142703. Epub 2008 Sep 11. J Pharmacol Exp Ther. 2008. PMID: 18787107
An update on the islet renin-angiotensin system.
Cheng Q, Leung PS. Cheng Q, et al. Among authors: leung ps. Peptides. 2011 May;32(5):1087-95. doi: 10.1016/j.peptides.2011.03.003. Epub 2011 Mar 17. Peptides. 2011. PMID: 21396973 Review.
459 results