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A unique anti-CD115 monoclonal antibody which inhibits osteolysis and skews human monocyte differentiation from M2-polarized macrophages toward dendritic cells.
Haegel H, Thioudellet C, Hallet R, Geist M, Menguy T, Le Pogam F, Marchand JB, Toh ML, Duong V, Calcei A, Settelen N, Preville X, Hennequi M, Grellier B, Ancian P, Rissanen J, Clayette P, Guillen C, Rooke R, Bonnefoy JY. Haegel H, et al. Among authors: bonnefoy jy. MAbs. 2013 Sep-Oct;5(5):736-47. doi: 10.4161/mabs.25743. Epub 2013 Jul 15. MAbs. 2013. PMID: 23924795 Free PMC article.
Therapeutic effects of anti-CD115 monoclonal antibody in mouse cancer models through dual inhibition of tumor-associated macrophages and osteoclasts.
Fend L, Accart N, Kintz J, Cochin S, Reymann C, Le Pogam F, Marchand JB, Menguy T, Slos P, Rooke R, Fournel S, Bonnefoy JY, Préville X, Haegel H. Fend L, et al. Among authors: bonnefoy jy. PLoS One. 2013 Sep 3;8(9):e73310. doi: 10.1371/journal.pone.0073310. eCollection 2013. PLoS One. 2013. PMID: 24019914 Free PMC article.
Bone- and cartilage-protective effects of a monoclonal antibody against colony-stimulating factor 1 receptor in experimental arthritis.
Toh ML, Bonnefoy JY, Accart N, Cochin S, Pohle S, Haegel H, De Meyer M, Zemmour C, Preville X, Guillen C, Thioudellet C, Ancian P, Lux A, Sehnert B, Nimmerjahn F, Voll RE, Schett G. Toh ML, et al. Among authors: bonnefoy jy. Arthritis Rheumatol. 2014 Nov;66(11):2989-3000. doi: 10.1002/art.38624. Arthritis Rheumatol. 2014. PMID: 24623505
Yeast virus-derived stimulator of the innate immune system augments the efficacy of virus vector-based immunotherapy.
Claudepierre MC, Hortelano J, Schaedler E, Kleinpeter P, Geist M, Remy-Ziller C, Brandely R, Tosch C, Laruelle L, Jawhari A, Menguy T, Marchand JB, Romby P, Schultz P, Hartmann G, Rooke R, Bonnefoy JY, Preville X, Rittner K. Claudepierre MC, et al. Among authors: bonnefoy jy. J Virol. 2014 May;88(10):5242-55. doi: 10.1128/JVI.03819-13. Epub 2014 Feb 26. J Virol. 2014. PMID: 24574403 Free PMC article.
205 results