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Structure- and reactivity-based development of covalent inhibitors of the activating and gatekeeper mutant forms of the epidermal growth factor receptor (EGFR).
Ward RA, Anderton MJ, Ashton S, Bethel PA, Box M, Butterworth S, Colclough N, Chorley CG, Chuaqui C, Cross DA, Dakin LA, Debreczeni JÉ, Eberlein C, Finlay MR, Hill GB, Grist M, Klinowska TC, Lane C, Martin S, Orme JP, Smith P, Wang F, Waring MJ. Ward RA, et al. Among authors: wang f. J Med Chem. 2013 Sep 12;56(17):7025-48. doi: 10.1021/jm400822z. Epub 2013 Aug 30. J Med Chem. 2013. PMID: 23930994
Structure-Cytotoxicity Relationships of Analogues of N14-Desacetoxytubulysin H.
Toader D, Wang F, Gingipalli L, Vasbinder M, Roth M, Mao S, Block M, Harper J, Thota S, Su M, Ma J, Bedian V, Kamal A. Toader D, et al. Among authors: wang f. J Med Chem. 2016 Dec 8;59(23):10781-10787. doi: 10.1021/acs.jmedchem.6b01023. Epub 2016 Nov 16. J Med Chem. 2016. PMID: 27809515
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
Shao L, Wang F, Malcolm SC, Ma J, Hewitt MC, Campbell UC, Bush LR, Spicer NA, Engel SR, Saraswat LD, Hardy LW, Koch P, Schreiber R, Spear KL, Varney MA. Shao L, et al. Among authors: wang f. Bioorg Med Chem. 2011 Jan 1;19(1):663-76. doi: 10.1016/j.bmc.2010.10.034. Epub 2010 Oct 21. Bioorg Med Chem. 2011. PMID: 21093273
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