Pattanayak V - Search Results

1

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.

Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK. Sander JD, et al. Among authors: pattanayak v. Nucleic Acids Res. 2013 Oct;41(19):e181. doi: 10.1093/nar/gkt716. Epub 2013 Aug 14. Nucleic Acids Res. 2013. PMID: 23945932 Free PMC article.

2

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection.

Pattanayak V, Ramirez CL, Joung JK, Liu DR. Pattanayak V, et al. Nat Methods. 2011 Aug 7;8(9):765-70. doi: 10.1038/nmeth.1670. Nat Methods. 2011. PMID: 21822273 Free PMC article.

3

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity.

Guilinger JP, Pattanayak V, Reyon D, Tsai SQ, Sander JD, Joung JK, Liu DR. Guilinger JP, et al. Among authors: pattanayak v. Nat Methods. 2014 Apr;11(4):429-35. doi: 10.1038/nmeth.2845. Epub 2014 Feb 16. Nat Methods. 2014. PMID: 24531420 Free PMC article.

4

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.

Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. Pattanayak V, et al. Nat Biotechnol. 2013 Sep;31(9):839-43. doi: 10.1038/nbt.2673. Epub 2013 Aug 11. Nat Biotechnol. 2013. PMID: 23934178 Free PMC article.

5

Determining the specificities of TALENs, Cas9, and other genome-editing enzymes.

Pattanayak V, Guilinger JP, Liu DR. Pattanayak V, et al. Methods Enzymol. 2014;546:47-78. doi: 10.1016/B978-0-12-801185-0.00003-9. Methods Enzymol. 2014. PMID: 25398335 Free PMC article. Review.

6

Directed evolution and substrate specificity profile of homing endonuclease I-SceI.

Doyon JB, Pattanayak V, Meyer CB, Liu DR. Doyon JB, et al. Among authors: pattanayak v. J Am Chem Soc. 2006 Feb 22;128(7):2477-84. doi: 10.1021/ja057519l. J Am Chem Soc. 2006. PMID: 16478204

7

Small molecule-triggered Cas9 protein with improved genome-editing specificity.

Davis KM, Pattanayak V, Thompson DB, Zuris JA, Liu DR. Davis KM, et al. Among authors: pattanayak v. Nat Chem Biol. 2015 May;11(5):316-8. doi: 10.1038/nchembio.1793. Epub 2015 Apr 6. Nat Chem Biol. 2015. PMID: 25848930 Free PMC article.

8

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

Kleinstiver BP, Pattanayak V, Prew MS, Tsai SQ, Nguyen NT, Zheng Z, Joung JK. Kleinstiver BP, et al. Among authors: pattanayak v. Nature. 2016 Jan 28;529(7587):490-5. doi: 10.1038/nature16526. Epub 2016 Jan 6. Nature. 2016. PMID: 26735016 Free PMC article.

9

CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN 1 M146L mutation.

Konstantinidis E, Molisak A, Perrin F, Streubel-Gallasch L, Fayad S, Kim DY, Petri K, Aryee MJ, Aguilar X, György B, Giedraitis V, Joung JK, Pattanayak V, Essand M, Erlandsson A, Berezovska O, Ingelsson M. Konstantinidis E, et al. Among authors: pattanayak v. Mol Ther Nucleic Acids. 2022 Mar 28;28:450-461. doi: 10.1016/j.omtn.2022.03.022. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35505961 Free PMC article.

10

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".

Lareau CA, Clement K, Hsu JY, Pattanayak V, Joung JK, Aryee MJ, Pinello L. Lareau CA, et al. Among authors: pattanayak v. Nat Methods. 2018 Apr;15(4):238-239. doi: 10.1038/nmeth.4541. Epub 2018 Mar 30. Nat Methods. 2018. PMID: 29600992 Free PMC article. No abstract available.

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