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L/N-type calcium channel blocker cilnidipine added to renin-angiotensin inhibition improves ambulatory blood pressure profile and suppresses cardiac hypertrophy in hypertension with chronic kidney disease.
Kanaoka T, Tamura K, Wakui H, Ohsawa M, Azushima K, Uneda K, Kobayashi R, Fujikawa T, Tsurumi-Ikeya Y, Maeda A, Yanagi M, Toya Y, Umemura S. Kanaoka T, et al. Among authors: kobayashi r. Int J Mol Sci. 2013 Aug 16;14(8):16866-81. doi: 10.3390/ijms140816866. Int J Mol Sci. 2013. PMID: 23959116 Free PMC article. Clinical Trial.
Addition of aliskiren to Angiotensin receptor blocker improves ambulatory blood pressure profile and cardiorenal function better than addition of benazepril in chronic kidney disease.
Ohsawa M, Tamura K, Kanaoka T, Wakui H, Maeda A, Dejima T, Azushima K, Uneda K, Kobayashi R, Tsurumi-Ikeya Y, Toya Y, Fujikawa T, Umemura S. Ohsawa M, et al. Among authors: kobayashi r. Int J Mol Sci. 2013 Jul 24;14(8):15361-75. doi: 10.3390/ijms140815361. Int J Mol Sci. 2013. PMID: 23887656 Free PMC article. Clinical Trial.
Bofu-tsu-shosan, an oriental herbal medicine, exerts a combinatorial favorable metabolic modulation including antihypertensive effect on a mouse model of human metabolic disorders with visceral obesity.
Azushima K, Tamura K, Wakui H, Maeda A, Ohsawa M, Uneda K, Kobayashi R, Kanaoka T, Dejima T, Fujikawa T, Yamashita A, Toya Y, Umemura S. Azushima K, et al. Among authors: kobayashi r. PLoS One. 2013 Oct 9;8(10):e75560. doi: 10.1371/journal.pone.0075560. eCollection 2013. PLoS One. 2013. PMID: 24130717 Free PMC article.
Activation of angiotensin II type 1 receptor-associated protein exerts an inhibitory effect on vascular hypertrophy and oxidative stress in angiotensin II-mediated hypertension.
Wakui H, Dejima T, Tamura K, Uneda K, Azuma K, Maeda A, Ohsawa M, Kanaoka T, Azushima K, Kobayashi R, Matsuda M, Yamashita A, Umemura S. Wakui H, et al. Among authors: kobayashi r. Cardiovasc Res. 2013 Dec 1;100(3):511-9. doi: 10.1093/cvr/cvt225. Epub 2013 Nov 4. Cardiovasc Res. 2013. PMID: 24189624
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.
Ohsawa M, Tamura K, Wakui H, Maeda A, Dejima T, Kanaoka T, Azushima K, Uneda K, Tsurumi-Ikeya Y, Kobayashi R, Matsuda M, Uchida S, Toya Y, Kobori H, Nishiyama A, Yamashita A, Ishikawa Y, Umemura S. Ohsawa M, et al. Among authors: kobayashi r. Kidney Int. 2014 Sep;86(3):570-81. doi: 10.1038/ki.2014.95. Epub 2014 Apr 2. Kidney Int. 2014. PMID: 24694992 Free PMC article.
Effects of single pill-based combination therapy of amlodipine and atorvastatin on within-visit blood pressure variability and parameters of renal and vascular function in hypertensive patients with chronic kidney disease.
Azushima K, Uneda K, Tamura K, Wakui H, Ohsawa M, Kobayashi R, Dejima T, Kanaoka T, Maeda A, Toya Y, Umemura S. Azushima K, et al. Among authors: kobayashi r. Biomed Res Int. 2014;2014:437087. doi: 10.1155/2014/437087. Epub 2014 Apr 8. Biomed Res Int. 2014. PMID: 24809050 Free PMC article.
Therapeutic impact of the single fixed-dose combination with a high-dose angiotensin-receptor blocker and a low-dose thiazide diuretic in the management of hypertension: awaiting further accumulation of clinical evidence.
Tamura K, Ohki K, Kobayashi R, Uneda K, Azushima K, Ohsawa M, Wakui H, Sakai M, Tokita Y, Umemura S. Tamura K, et al. Among authors: kobayashi r. Hypertens Res. 2014 Dec;37(12):1032-4. doi: 10.1038/hr.2014.130. Epub 2014 Sep 4. Hypertens Res. 2014. PMID: 25185832 No abstract available.
2,085 results