Singh I - Search Results

1

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.

Singh I, Sagare AP, Coma M, Perlmutter D, Gelein R, Bell RD, Deane RJ, Zhong E, Parisi M, Ciszewski J, Kasper RT, Deane R. Singh I, et al. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14771-6. doi: 10.1073/pnas.1302212110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959870 Free PMC article.

2

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells.

Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV. Bell RD, et al. Among authors: singh i. Nat Cell Biol. 2009 Feb;11(2):143-53. doi: 10.1038/ncb1819. Epub 2008 Dec 21. Nat Cell Biol. 2009. PMID: 19098903 Free PMC article.

3

Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity.

Guo H, Singh I, Wang Y, Deane R, Barrett T, Fernández JA, Chow N, Griffin JH, Zlokovic BV. Guo H, et al. Among authors: singh i. Eur J Neurosci. 2009 Mar;29(6):1119-30. doi: 10.1111/j.1460-9568.2009.06664.x. Eur J Neurosci. 2009. Retraction in: Eur J Neurosci. 2024 Nov;60(10):6588. doi: 10.1111/ejn.16587 PMID: 19302148 Free PMC article. Retracted.

4

Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells.

Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan M, Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N, Castellino FJ, Stojanovic K, Cleveland DW, Zlokovic BV. Zhong Z, et al. Among authors: singh i. J Clin Invest. 2009 Nov;119(11):3437-49. doi: 10.1172/JCI38476. Epub 2009 Oct 19. J Clin Invest. 2009. PMID: 19841542 Free PMC article.

5

Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor.

Zhu D, Wang Y, Singh I, Bell RD, Deane R, Zhong Z, Sagare A, Winkler EA, Zlokovic BV. Zhu D, et al. Among authors: singh i. Blood. 2010 Jun 10;115(23):4963-72. doi: 10.1182/blood-2010-01-262386. Epub 2010 Mar 26. Blood. 2010. PMID: 20348395 Free PMC article.

6

Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging.

Bell RD, Winkler EA, Sagare AP, Singh I, LaRue B, Deane R, Zlokovic BV. Bell RD, et al. Among authors: singh i. Neuron. 2010 Nov 4;68(3):409-27. doi: 10.1016/j.neuron.2010.09.043. Neuron. 2010. PMID: 21040844 Free PMC article.

7

A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease.

Deane R, Singh I, Sagare AP, Bell RD, Ross NT, LaRue B, Love R, Perry S, Paquette N, Deane RJ, Thiyagarajan M, Zarcone T, Fritz G, Friedman AE, Miller BL, Zlokovic BV. Deane R, et al. Among authors: singh i. J Clin Invest. 2012 Apr;122(4):1377-92. doi: 10.1172/JCI58642. Epub 2012 Mar 12. J Clin Invest. 2012. PMID: 22406537 Free PMC article.

8

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.

Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV. Bell RD, et al. Among authors: singh i. Nature. 2012 May 16;485(7399):512-6. doi: 10.1038/nature11087. Nature. 2012. PMID: 22622580 Free PMC article.

9

A lipoprotein receptor cluster IV mutant preferentially binds amyloid-β and regulates its clearance from the mouse brain.

Sagare AP, Bell RD, Srivastava A, Sengillo JD, Singh I, Nishida Y, Chow N, Zlokovic BV. Sagare AP, et al. Among authors: singh i. J Biol Chem. 2013 May 24;288(21):15154-66. doi: 10.1074/jbc.M112.439570. Epub 2013 Apr 11. J Biol Chem. 2013. PMID: 23580652 Free PMC article.

10

Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury.

Iliff JJ, Chen MJ, Plog BA, Zeppenfeld DM, Soltero M, Yang L, Singh I, Deane R, Nedergaard M. Iliff JJ, et al. Among authors: singh i. J Neurosci. 2014 Dec 3;34(49):16180-93. doi: 10.1523/JNEUROSCI.3020-14.2014. J Neurosci. 2014. PMID: 25471560 Free PMC article.

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