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Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3',2':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2',3':4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5'-monophosphate-activated protein kinase (AMPK).
Gu Z, Wu L, Duan Y, Wang J, Zhou S, Li J, Chen K, Li J, Liu H. Gu Z, et al. Bioorg Med Chem. 2018 May 1;26(8):2017-2027. doi: 10.1016/j.bmc.2018.02.052. Epub 2018 Mar 12. Bioorg Med Chem. 2018. PMID: 29545016
885 results