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MLST revisited: the gene-by-gene approach to bacterial genomics.
Maiden MC, Jansen van Rensburg MJ, Bray JE, Earle SG, Ford SA, Jolley KA, McCarthy ND. Maiden MC, et al. Among authors: earle sg. Nat Rev Microbiol. 2013 Oct;11(10):728-36. doi: 10.1038/nrmicro3093. Epub 2013 Sep 2. Nat Rev Microbiol. 2013. PMID: 23979428 Free PMC article. Review.
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis.
Sonnenkalb L, Carter JJ, Spitaleri A, Iqbal Z, Hunt M, Malone KM, Utpatel C, Cirillo DM, Rodrigues C, Nilgiriwala KS, Fowler PW, Merker M, Niemann S; Comprehensive Resistance Prediction for Tuberculosis: an International Consortium. Sonnenkalb L, et al. Lancet Microbe. 2023 May;4(5):e358-e368. doi: 10.1016/S2666-5247(23)00002-2. Epub 2023 Mar 29. Lancet Microbe. 2023. PMID: 37003285 Free PMC article.
Identifying lineage effects when controlling for population structure improves power in bacterial association studies.
Earle SG, Wu CH, Charlesworth J, Stoesser N, Gordon NC, Walker TM, Spencer CCA, Iqbal Z, Clifton DA, Hopkins KL, Woodford N, Smith EG, Ismail N, Llewelyn MJ, Peto TE, Crook DW, McVean G, Walker AS, Wilson DJ. Earle SG, et al. Nat Microbiol. 2016 Apr 4;1:16041. doi: 10.1038/nmicrobiol.2016.41. Nat Microbiol. 2016. PMID: 27572646 Free PMC article.
Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis.
Earle SG, Lobanovska M, Lavender H, Tang C, Exley RM, Ramos-Sevillano E, Browning DF, Kostiou V, Harrison OB, Bratcher HB, Varani G, Tang CM, Wilson DJ, Maiden MCJ. Earle SG, et al. PLoS Pathog. 2021 Oct 18;17(10):e1009992. doi: 10.1371/journal.ppat.1009992. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34662348 Free PMC article.
Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis.
Bradley P, Gordon NC, Walker TM, Dunn L, Heys S, Huang B, Earle S, Pankhurst LJ, Anson L, de Cesare M, Piazza P, Votintseva AA, Golubchik T, Wilson DJ, Wyllie DH, Diel R, Niemann S, Feuerriegel S, Kohl TA, Ismail N, Omar SV, Smith EG, Buck D, McVean G, Walker AS, Peto TE, Crook DW, Iqbal Z. Bradley P, et al. Nat Commun. 2015 Dec 21;6:10063. doi: 10.1038/ncomms10063. Nat Commun. 2015. PMID: 26686880 Free PMC article.
Targeted control of pneumolysin production by a mobile genetic element in Streptococcus pneumoniae.
Stevens EJ, Morse DJ, Bonini D, Duggan S, Brignoli T, Recker M, Lees JA, Croucher NJ, Bentley S, Wilson DJ, Earle SG, Dixon R, Nobbs A, Jenkinson H, van Opijnen T, Thibault D, Wilkinson OJ, Dillingham MS, Carlile S, McLoughlin RM, Massey RC. Stevens EJ, et al. Among authors: earle sg. Microb Genom. 2022 Apr;8(4):000784. doi: 10.1099/mgen.0.000784. Microb Genom. 2022. PMID: 35416147 Free PMC article.
Corrigendum: Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis.
Bradley P, Gordon NC, Walker TM, Dunn L, Heys S, Huang B, Earle S, Pankhurst LJ, Anson L, de Cesare M, Piazza P, Votintseva AA, Golubchik T, Wilson DJ, Wyllie DH, Diel R, Niemann S, Feuerriegel S, Kohl TA, Ismail N, Omar SV, Smith EG, Buck D, McVean G, Walker AS, Peto TE, Crook DW, Iqbal Z. Bradley P, et al. Nat Commun. 2016 Apr 20;7:11465. doi: 10.1038/ncomms11465. Nat Commun. 2016. PMID: 27095245 Free PMC article. No abstract available.
Panton-Valentine leucocidin is the key determinant of Staphylococcus aureus pyomyositis in a bacterial GWAS.
Young BC, Earle SG, Soeng S, Sar P, Kumar V, Hor S, Sar V, Bousfield R, Sanderson ND, Barker L, Stoesser N, Emary KR, Parry CM, Nickerson EK, Turner P, Bowden R, Crook DW, Wyllie DH, Day NP, Wilson DJ, Moore CE. Young BC, et al. Among authors: earle sg. Elife. 2019 Feb 22;8:e42486. doi: 10.7554/eLife.42486. Elife. 2019. PMID: 30794157 Free PMC article.
24 results