Loughran P - Search Results

1

Experimental sepsis-induced mitochondrial biogenesis is dependent on autophagy, TLR4, and TLR9 signaling in liver.

Carchman EH, Whelan S, Loughran P, Mollen K, Stratamirovic S, Shiva S, Rosengart MR, Zuckerbraun BS. Carchman EH, et al. Among authors: loughran p. FASEB J. 2013 Dec;27(12):4703-11. doi: 10.1096/fj.13-229476. Epub 2013 Aug 27. FASEB J. 2013. PMID: 23982147 Free PMC article.

2

Carbon monoxide protects hepatocytes from TNF-alpha/Actinomycin D by inhibition of the caspase-8-mediated apoptotic pathway.

Kim HS, Loughran PA, Kim PK, Billiar TR, Zuckerbraun BS. Kim HS, et al. Biochem Biophys Res Commun. 2006 Jun 16;344(4):1172-8. doi: 10.1016/j.bbrc.2006.03.180. Epub 2006 Apr 6. Biochem Biophys Res Commun. 2006. PMID: 16647044

3

Carbon monoxide activates NF-kappaB via ROS generation and Akt pathways to protect against cell death of hepatocytes.

Kim HS, Loughran PA, Rao J, Billiar TR, Zuckerbraun BS. Kim HS, et al. Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G146-G152. doi: 10.1152/ajpgi.00105.2007. Epub 2008 May 22. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18497334 Free article.

4

Systemic inflammation and liver injury following hemorrhagic shock and peripheral tissue trauma involve functional TLR9 signaling on bone marrow-derived cells and parenchymal cells.

Gill R, Ruan X, Menzel CL, Namkoong S, Loughran P, Hackam DJ, Billiar TR. Gill R, et al. Among authors: loughran p. Shock. 2011 Feb;35(2):164-70. doi: 10.1097/SHK.0b013e3181eddcab. Shock. 2011. PMID: 20577143 Free PMC article.

5

Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice.

Carchman EH, Rao J, Loughran PA, Rosengart MR, Zuckerbraun BS. Carchman EH, et al. Hepatology. 2011 Jun;53(6):2053-62. doi: 10.1002/hep.24324. Epub 2011 May 2. Hepatology. 2011. PMID: 21437926 Free PMC article.

6

Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14.

Kim S, Kim SY, Pribis JP, Lotze M, Mollen KP, Shapiro R, Loughran P, Scott MJ, Billiar TR. Kim S, et al. Among authors: loughran p. Mol Med. 2013 May 20;19(1):88-98. doi: 10.2119/molmed.2012.00306. Mol Med. 2013. PMID: 23508573 Free PMC article.

7

Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type-specific functions of TLR4 during sepsis.

Deng M, Scott MJ, Loughran P, Gibson G, Sodhi C, Watkins S, Hackam D, Billiar TR. Deng M, et al. Among authors: loughran p. J Immunol. 2013 May 15;190(10):5152-60. doi: 10.4049/jimmunol.1300496. Epub 2013 Apr 5. J Immunol. 2013. PMID: 23562812 Free PMC article.

8

Caspase 1 activation is protective against hepatocyte cell death by up-regulating beclin 1 protein and mitochondrial autophagy in the setting of redox stress.

Sun Q, Gao W, Loughran P, Shapiro R, Fan J, Billiar TR, Scott MJ. Sun Q, et al. Among authors: loughran p. J Biol Chem. 2013 May 31;288(22):15947-58. doi: 10.1074/jbc.M112.426791. Epub 2013 Apr 15. J Biol Chem. 2013. PMID: 23589298 Free PMC article.

9

Augmenting autophagy to treat acute kidney injury during endotoxemia in mice.

Howell GM, Gomez H, Collage RD, Loughran P, Zhang X, Escobar DA, Billiar TR, Zuckerbraun BS, Rosengart MR. Howell GM, et al. Among authors: loughran p. PLoS One. 2013 Jul 30;8(7):e69520. doi: 10.1371/journal.pone.0069520. Print 2013. PLoS One. 2013. PMID: 23936035 Free PMC article.

10

Delayed inhaled carbon monoxide mediates the regression of established neointimal lesions.

Madigan M, Entabi F, Zuckerbraun B, Loughran P, Tzeng E. Madigan M, et al. Among authors: loughran p. J Vasc Surg. 2015 Apr;61(4):1026-33. doi: 10.1016/j.jvs.2013.11.072. Epub 2014 Jan 11. J Vasc Surg. 2015. PMID: 24418641 Free PMC article.

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