Yotsu-Yamashita M - Search Results

1

Synthesis of saxitoxin derivatives bearing guanidine and urea groups at C13 and evaluation of their inhibitory activity on voltage-gated sodium channels.

Akimoto T, Masuda A, Yotsu-Yamashita M, Hirokawa T, Nagasawa K. Akimoto T, et al. Org Biomol Chem. 2013 Oct 14;11(38):6642-9. doi: 10.1039/c3ob41398e. Epub 2013 Aug 30. Org Biomol Chem. 2013. PMID: 23989458

2

The quite low cross-reactivity of Kawatsu's anti-tetrodotoxin monoclonal antibody to 5,6,11-trideoxytetrodotoxin, 11-nortetrodotoxin-6(S)-ol, and 11-oxotetrodotoxin, the major tetrodotoxin analogues in pufferfish.

Yamaki K, Sato K, Kudo Y, Cho Y, Konoki K, Takatani T, Arakawa O, Kawatsu K, Yotsu-Yamashita M. Yamaki K, et al. Among authors: yotsu yamashita m. Toxicon. 2023 Apr;226:107081. doi: 10.1016/j.toxicon.2023.107081. Epub 2023 Mar 8. Toxicon. 2023. PMID: 36898506

3

Temporal variation in the concentrations and profiles of paralytic shellfish toxins and tetrodotoxin in scallop (Mizuhopecten yessoensis) and bloody clam (Anadara broughtonii) collected from the coast of Miyagi Prefecture, Japan.

Shingai T, Chiba Y, Kondo M, Yotsu-Yamashita M. Shingai T, et al. Among authors: yotsu yamashita m. Toxicon. 2024 May 28;243:107710. doi: 10.1016/j.toxicon.2024.107710. Epub 2024 Apr 4. Toxicon. 2024. PMID: 38579982

4

Synthesis of skeletal analogues of saxitoxin derivatives and evaluation of their inhibitory activity on sodium ion channels Na(V)1.4 and Na(V)1.5.

Shinohara R, Akimoto T, Iwamoto O, Hirokawa T, Yotsu-Yamashita M, Yamaoka K, Nagasawa K. Shinohara R, et al. Chemistry. 2011 Oct 17;17(43):12144-52. doi: 10.1002/chem.201101058. Epub 2011 Sep 16. Chemistry. 2011. PMID: 21922571

5

Synthesis of crambescin B carboxylic acid, a potent inhibitor of voltage-gated sodium channels.

Nakazaki A, Ishikawa Y, Sawayama Y, Yotsu-Yamashita M, Nishikawa T. Nakazaki A, et al. Org Biomol Chem. 2014 Jan 7;12(1):53-6. doi: 10.1039/c3ob42017e. Epub 2013 Nov 11. Org Biomol Chem. 2014. PMID: 24216693

6

Synthesis and identification of proposed biosynthetic intermediates of saxitoxin in the cyanobacterium Anabaena circinalis (TA04) and the dinoflagellate Alexandrium tamarense (Axat-2).

Tsuchiya S, Cho Y, Konoki K, Nagasawa K, Oshima Y, Yotsu-Yamashita M. Tsuchiya S, et al. Org Biomol Chem. 2014 May 21;12(19):3016-20. doi: 10.1039/c4ob00071d. Org Biomol Chem. 2014. PMID: 24718696

7

Synthesis of a tricyclic bisguanidine compound structurally related to saxitoxin and its identification in paralytic shellfish toxin-producing microorganisms.

Tsuchiya S, Cho Y, Konoki K, Nagasawa K, Oshima Y, Yotsu-Yamashita M. Tsuchiya S, et al. Chemistry. 2015 May 18;21(21):7835-40. doi: 10.1002/chem.201500064. Epub 2015 Apr 14. Chemistry. 2015. PMID: 25873235

8

Biosynthetic route towards saxitoxin and shunt pathway.

Tsuchiya S, Cho Y, Konoki K, Nagasawa K, Oshima Y, Yotsu-Yamashita M. Tsuchiya S, et al. Sci Rep. 2016 Feb 4;6:20340. doi: 10.1038/srep20340. Sci Rep. 2016. PMID: 26842222 Free PMC article.

9

Asymmetric synthesis of crambescin A-C carboxylic acids and their inhibitory activity on voltage-gated sodium channels.

Nakazaki A, Nakane Y, Ishikawa Y, Yotsu-Yamashita M, Nishikawa T. Nakazaki A, et al. Org Biomol Chem. 2016 Jun 21;14(23):5304-9. doi: 10.1039/c6ob00914j. Epub 2016 May 24. Org Biomol Chem. 2016. PMID: 27215973

10

Total Synthesis of 11-Saxitoxinethanoic Acid and Evaluation of its Inhibitory Activity on Voltage-Gated Sodium Channels.

Wang C, Oki M, Nishikawa T, Harada D, Yotsu-Yamashita M, Nagasawa K. Wang C, et al. Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11600-3. doi: 10.1002/anie.201604155. Epub 2016 Aug 11. Angew Chem Int Ed Engl. 2016. PMID: 27512941 Free article.

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