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EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.
Sánchez-Tilló E, Liu Y, de Barrios O, Siles L, Fanlo L, Cuatrecasas M, Darling DS, Dean DC, Castells A, Postigo A. Sánchez-Tilló E, et al. Cell Mol Life Sci. 2012 Oct;69(20):3429-56. doi: 10.1007/s00018-012-1122-2. Epub 2012 Sep 4. Cell Mol Life Sci. 2012. PMID: 22945800 Free PMC article. Review.
Sequential inductions of the ZEB1 transcription factor caused by mutation of Rb and then Ras proteins are required for tumor initiation and progression.
Liu Y, Sánchez-Tilló E, Lu X, Huang L, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Postigo A, Dean DC. Liu Y, et al. Among authors: sanchez tillo e. J Biol Chem. 2013 Apr 19;288(16):11572-80. doi: 10.1074/jbc.M112.434951. Epub 2013 Feb 26. J Biol Chem. 2013. PMID: 23443660 Free PMC article.
Rb1 family mutation is sufficient for sarcoma initiation.
Liu Y, Sánchez-Tilló E, Lu X, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Postigo A, Dean DC. Liu Y, et al. Among authors: sanchez tillo e. Nat Commun. 2013;4:2650. doi: 10.1038/ncomms3650. Nat Commun. 2013. PMID: 24150016 Free article.
28 results