Siles L - Search Results

1

The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma.

Sánchez-Tilló E, Fanlo L, Siles L, Montes-Moreno S, Moros A, Chiva-Blanch G, Estruch R, Martinez A, Colomer D, Győrffy B, Roué G, Postigo A. Sánchez-Tilló E, et al. Among authors: siles l. Cell Death Differ. 2014 Feb;21(2):247-57. doi: 10.1038/cdd.2013.123. Epub 2013 Sep 6. Cell Death Differ. 2014. PMID: 24013721 Free PMC article.

2

Expanding roles of ZEB factors in tumorigenesis and tumor progression.

Sánchez-Tilló E, Siles L, de Barrios O, Cuatrecasas M, Vaquero EC, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: siles l. Am J Cancer Res. 2011;1(7):897-912. Epub 2011 Aug 20. Am J Cancer Res. 2011. PMID: 22016835 Free PMC article.

3

β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.

Sánchez-Tilló E, de Barrios O, Siles L, Cuatrecasas M, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: siles l. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19204-9. doi: 10.1073/pnas.1108977108. Epub 2011 Nov 11. Proc Natl Acad Sci U S A. 2011. PMID: 22080605 Free PMC article.

4

EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.

Sánchez-Tilló E, Liu Y, de Barrios O, Siles L, Fanlo L, Cuatrecasas M, Darling DS, Dean DC, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: siles l. Cell Mol Life Sci. 2012 Oct;69(20):3429-56. doi: 10.1007/s00018-012-1122-2. Epub 2012 Sep 4. Cell Mol Life Sci. 2012. PMID: 22945800 Free PMC article. Review.

5

ZEB1 imposes a temporary stage-dependent inhibition of muscle gene expression and differentiation via CtBP-mediated transcriptional repression.

Siles L, Sánchez-Tilló E, Lim JW, Darling DS, Kroll KL, Postigo A. Siles L, et al. Mol Cell Biol. 2013 Apr;33(7):1368-82. doi: 10.1128/MCB.01259-12. Epub 2013 Jan 22. Mol Cell Biol. 2013. PMID: 23339872 Free PMC article.

6

ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1.

Sánchez-Tilló E, de Barrios O, Siles L, Amendola PG, Darling DS, Cuatrecasas M, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: siles l. Clin Cancer Res. 2013 Mar 1;19(5):1071-82. doi: 10.1158/1078-0432.CCR-12-2675. Epub 2013 Jan 22. Clin Cancer Res. 2013. PMID: 23340304

7

ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.

de Barrios O, Győrffy B, Fernández-Aceñero MJ, Sánchez-Tilló E, Sánchez-Moral L, Siles L, Esteve-Arenys A, Roué G, Casal JI, Darling DS, Castells A, Postigo A. de Barrios O, et al. Among authors: siles l. Gut. 2017 Apr;66(4):666-682. doi: 10.1136/gutjnl-2015-310838. Epub 2016 Dec 13. Gut. 2017. PMID: 27965283

8

Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells.

Liu Y, Siles L, Lu X, Dean KC, Cuatrecasas M, Postigo A, Dean DC. Liu Y, et al. Among authors: siles l. Nat Commun. 2018 Jun 21;9(1):2424. doi: 10.1038/s41467-018-04663-1. Nat Commun. 2018. PMID: 29930325 Free PMC article.

9

Epigenetically distinct sister chromatids and asymmetric generation of tumor initiating cells.

Liu Y, Siles L, Postigo A, Dean DC. Liu Y, et al. Among authors: siles l. Cell Cycle. 2018;17(18):2221-2229. doi: 10.1080/15384101.2018.1532254. Epub 2018 Oct 13. Cell Cycle. 2018. PMID: 30290712 Free PMC article. Review.

10

Regulation of muscle atrophy-related genes by the opposing transcriptional activities of ZEB1/CtBP and FOXO3.

Ninfali C, Siles L, Darling DS, Postigo A. Ninfali C, et al. Among authors: siles l. Nucleic Acids Res. 2018 Nov 16;46(20):10697-10708. doi: 10.1093/nar/gky835. Nucleic Acids Res. 2018. PMID: 30304480 Free PMC article.

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