Houghten RA - Search Results

1

Dissociation of antimicrobial and hemolytic activities of gramicidin S through N-methylation modification.

Li Y, Bionda N, Yongye A, Geer P, Stawikowski M, Cudic P, Martinez K, Houghten RA. Li Y, et al. Among authors: houghten ra. ChemMedChem. 2013 Nov;8(11):1865-72. doi: 10.1002/cmdc.201300232. Epub 2013 Sep 10. ChemMedChem. 2013. PMID: 24023000

2

Synthesis of cyclic peptides through direct aminolysis of peptide thioesters catalyzed by imidazole in aqueous organic solutions.

Li Y, Yongye A, Giulianotti M, Martinez-Mayorga K, Yu Y, Houghten RA. Li Y, et al. Among authors: houghten ra. J Comb Chem. 2009 Nov-Dec;11(6):1066-72. doi: 10.1021/cc900100z. J Comb Chem. 2009. PMID: 19894764 Free PMC article.

3

Identification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents.

Li Y, Bionda N, Fleeman R, Wang H, Ozawa A, Houghten RA, Shaw L. Li Y, et al. Among authors: houghten ra. Bioorg Med Chem. 2016 Nov 1;24(21):5633-5638. doi: 10.1016/j.bmc.2016.09.027. Epub 2016 Sep 12. Bioorg Med Chem. 2016. PMID: 27663549 Free PMC article.

4

Modeling of peptides containing D-amino acids: implications on cyclization.

Yongye AB, Li Y, Giulianotti MA, Yu Y, Houghten RA, Martínez-Mayorga K. Yongye AB, et al. Among authors: houghten ra. J Comput Aided Mol Des. 2009 Sep;23(9):677-89. doi: 10.1007/s10822-009-9295-y. Epub 2009 Jul 11. J Comput Aided Mol Des. 2009. PMID: 19593648

5

Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities.

Hu M, Giulianotti MA, McLaughlin JP, Shao J, Debevec G, Maida LE, Geer P, Cazares M, Misler J, Li L, Dooley C, Ganno ML, Eans SO, Mizrachi E, Santos RG, Yongye AB, Houghten RA, Yu Y. Hu M, et al. Among authors: houghten ra. Eur J Med Chem. 2015 Mar 6;92:270-81. doi: 10.1016/j.ejmech.2014.12.049. Epub 2014 Dec 29. Eur J Med Chem. 2015. PMID: 25559207

6

One-pot high-throughput synthesis of beta-turn cyclic peptidomimetics via "volatilizable" supports.

Li Y, Yu Y, Giulianotti M, Houghten RA. Li Y, et al. Among authors: houghten ra. J Org Chem. 2009 Mar 6;74(5):2183-5. doi: 10.1021/jo802583t. J Org Chem. 2009. PMID: 19173629 Free PMC article.

7

Conformational landscape of platinum(II)-tetraamine complexes: DFT and NBO studies.

Yongye AB, Giulianotti MA, Nefzi A, Houghten RA, Martínez-Mayorga K. Yongye AB, et al. Among authors: houghten ra. J Comput Aided Mol Des. 2010 Mar;24(3):225-35. doi: 10.1007/s10822-010-9328-6. Epub 2010 Mar 24. J Comput Aided Mol Des. 2010. PMID: 20333441

8

Macrolactonization of peptide thioesters catalyzed by imidazole and its application in the synthesis of kahalalide B and analogues.

Li Y, Giulionatti M, Houghten RA. Li Y, et al. Among authors: houghten ra. Org Lett. 2010 May 21;12(10):2250-3. doi: 10.1021/ol100596p. Org Lett. 2010. PMID: 20426464 Free PMC article.

9

Potent μ-Opioid Receptor Agonists from Cyclic Peptides Tyr-c[D-Lys-Xxx-Tyr-Gly]: Synthesis, Biological, and Structural Evaluation.

Li Y, Cazares M, Wu J, Houghten RA, Toll L, Dooley C. Li Y, et al. Among authors: houghten ra. J Med Chem. 2016 Feb 11;59(3):1239-45. doi: 10.1021/acs.jmedchem.5b01899. Epub 2016 Jan 29. J Med Chem. 2016. PMID: 26789491

10

Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands.

Yongye AB, Appel JR, Giulianotti MA, Dooley CT, Medina-Franco JL, Nefzi A, Houghten RA, Martínez-Mayorga K. Yongye AB, et al. Among authors: houghten ra. Bioorg Med Chem. 2009 Aug 1;17(15):5583-97. doi: 10.1016/j.bmc.2009.06.026. Epub 2009 Jun 21. Bioorg Med Chem. 2009. PMID: 19576786 Free PMC article.

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