Kumar TS - Search Results

1

Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA.

Sau SP, Madsen AS, Podbevsek P, Andersen NK, Kumar TS, Andersen S, Rathje RL, Anderson BA, Guenther DC, Karmakar S, Kumar P, Plavec J, Wengel J, Hrdlicka PJ. Sau SP, et al. Among authors: kumar ts, kumar p. J Org Chem. 2013 Oct 4;78(19):9560-70. doi: 10.1021/jo4015936. Epub 2013 Sep 25. J Org Chem. 2013. PMID: 24032477 Free PMC article.

2

Targeting of mixed sequence double-stranded DNA using pyrene-functionalized 2'-amino-alpha-l-LNA.

Hrdlicka PJ, Kumar TS, Wengel J. Hrdlicka PJ, et al. Among authors: kumar ts. Chem Commun (Camb). 2005 Sep 14;(34):4279-81. doi: 10.1039/b506986f. Epub 2005 Jul 21. Chem Commun (Camb). 2005. PMID: 16113721

3

Synthesis and hybridization studies of 2'-amino-alpha-L-LNA and tetracyclic "locked LNA".

Kumar TS, Madsen AS, Wengel J, Hrdlicka PJ. Kumar TS, et al. J Org Chem. 2006 May 26;71(11):4188-201. doi: 10.1021/jo060331f. J Org Chem. 2006. PMID: 16709060

4

Nucleic acid structural engineering using pyrene-functionalized 2'-amino-alpha-L-LNA monomers and abasic sites.

Kumar TS, Madsen AS, Østergaard ME, Wengel J, Hrdlicka PJ. Kumar TS, et al. J Org Chem. 2008 Sep 19;73(18):7060-6. doi: 10.1021/jo800551j. Epub 2008 Aug 19. J Org Chem. 2008. PMID: 18710289

5

Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting.

Kumar TS, Madsen AS, Østergaard ME, Sau SP, Wengel J, Hrdlicka PJ. Kumar TS, et al. J Org Chem. 2009 Feb 6;74(3):1070-81. doi: 10.1021/jo802037v. J Org Chem. 2009. PMID: 19108636 Free PMC article.

6

Invader LNA: efficient targeting of short double stranded DNA.

Sau SP, Kumar TS, Hrdlicka PJ. Sau SP, et al. Among authors: kumar ts. Org Biomol Chem. 2010 May 7;8(9):2028-36. doi: 10.1039/b923465a. Epub 2010 Mar 4. Org Biomol Chem. 2010. PMID: 20401378 Free PMC article.

7

Synthesis, nucleic acid hybridization properties and molecular modelling studies of conformationally restricted 3'-O,4'-C-methylene-linked alpha-L-ribonucleotides.

Madsen AS, Hrdlicka PJ, Kumar TS, Wengel J. Madsen AS, et al. Among authors: kumar ts. Carbohydr Res. 2006 Jul 24;341(10):1398-407. doi: 10.1016/j.carres.2006.04.010. Epub 2006 May 18. Carbohydr Res. 2006. PMID: 16709404

8

2'-N-(pyren-1-yl)acetyl-2'-amino-alpha-L-LNA: synthesis and detection of single nucleotide mismatches in DNA and RNA targets.

Kumar TS, Wengel J, Hrdlicka PJ. Kumar TS, et al. Chembiochem. 2007 Jul 9;8(10):1122-5. doi: 10.1002/cbic.200700144. Chembiochem. 2007. PMID: 17551917 No abstract available.

9

Synthesis and biophysical studies of N2'-functionalized 2'-amino-alpha-L-LNA.

Kumar TS, Madsen AS, Wengel J, Hrdlicka PJ. Kumar TS, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1403-5. doi: 10.1080/15257770701538841. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066792

10

Pyrene-functionalized 2'-amino-alpha-L-LNA as potential diagnostic probes.

Kumar TS, Wengel J, Hrdlicka PJ. Kumar TS, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1407-9. doi: 10.1080/15257770701538908. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066793

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