Cardozo T - Search Results

1

Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.

Pavlides SC, Huang KT, Reid DA, Wu L, Blank SV, Mittal K, Guo L, Rothenberg E, Rueda B, Cardozo T, Gold LI. Pavlides SC, et al. Among authors: cardozo t. Endocrinology. 2013 Nov;154(11):4030-45. doi: 10.1210/en.2013-1757. Epub 2013 Sep 13. Endocrinology. 2013. PMID: 24035998 Free PMC article.

2

Specific small molecule inhibitors of Skp2-mediated p27 degradation.

Wu L, Grigoryan AV, Li Y, Hao B, Pagano M, Cardozo TJ. Wu L, et al. Chem Biol. 2012 Dec 21;19(12):1515-24. doi: 10.1016/j.chembiol.2012.09.015. Chem Biol. 2012. PMID: 23261596 Free PMC article.

3

The SCF ubiquitin ligase: insights into a molecular machine.

Cardozo T, Pagano M. Cardozo T, et al. Nat Rev Mol Cell Biol. 2004 Sep;5(9):739-51. doi: 10.1038/nrm1471. Nat Rev Mol Cell Biol. 2004. PMID: 15340381 Review.

4

Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes.

Cardozo T, Pagano M. Cardozo T, et al. BMC Biochem. 2007 Nov 22;8 Suppl 1(Suppl 1):S9. doi: 10.1186/1471-2091-8-S1-S9. BMC Biochem. 2007. PMID: 18047746 Free PMC article. Review.

5

Farnesyl pyrophosphate is a novel transcriptional activator for a subset of nuclear hormone receptors.

Das S, Schapira M, Tomic-Canic M, Goyanka R, Cardozo T, Samuels HH. Das S, et al. Among authors: cardozo t. Mol Endocrinol. 2007 Nov;21(11):2672-86. doi: 10.1210/me.2007-0080. Epub 2007 Jul 31. Mol Endocrinol. 2007. PMID: 17666588

6

Chemical probes of Skp2-mediated p27 ubiquitylation and degradation.

Lough L, Sherman D, Ni E, Young LM, Hao B, Cardozo T. Lough L, et al. Among authors: cardozo t. Medchemcomm. 2018 Jun 11;9(7):1093-1104. doi: 10.1039/c8md00140e. eCollection 2018 Jul 1. Medchemcomm. 2018. PMID: 30108998 Free PMC article. Review.

7

Nuclear receptor engineering based on novel structure activity relationships revealed by farnesyl pyrophosphate.

Goyanka R, Das S, Samuels HH, Cardozo T. Goyanka R, et al. Among authors: cardozo t. Protein Eng Des Sel. 2010 Nov;23(11):809-15. doi: 10.1093/protein/gzq056. Epub 2010 Sep 3. Protein Eng Des Sel. 2010. PMID: 20817759 Free PMC article.

8

An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway.

Gonsalves FC, Klein K, Carson BB, Katz S, Ekas LA, Evans S, Nagourney R, Cardozo T, Brown AM, DasGupta R. Gonsalves FC, et al. Among authors: cardozo t. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):5954-63. doi: 10.1073/pnas.1017496108. Epub 2011 Mar 10. Proc Natl Acad Sci U S A. 2011. PMID: 21393571 Free PMC article.

9

Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.

Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T, Lasorella A, Iavarone A, Chang S, Hernando E, Pagano M. Guardavaccaro D, et al. Among authors: cardozo t. Nature. 2008 Mar 20;452(7185):365-9. doi: 10.1038/nature06641. Nature. 2008. PMID: 18354482 Free PMC article.

10

Structural determinants of PERK inhibitor potency and selectivity.

Wang H, Blais J, Ron D, Cardozo T. Wang H, et al. Among authors: cardozo t. Chem Biol Drug Des. 2010 Dec;76(6):480-95. doi: 10.1111/j.1747-0285.2010.01048.x. Chem Biol Drug Des. 2010. PMID: 21070610 Free PMC article.

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