Wyffels L - Search Results

1

N-acetylcysteine- and MK-801-induced changes in glutamate levels do not affect in vivo binding of metabotropic glutamate 5 receptor radioligand 11C-ABP688 in rat brain.

Wyckhuys T, Verhaeghe J, Wyffels L, Langlois X, Schmidt M, Stroobants S, Staelens S. Wyckhuys T, et al. Among authors: wyffels l. J Nucl Med. 2013 Nov;54(11):1954-61. doi: 10.2967/jnumed.113.121608. Epub 2013 Sep 19. J Nucl Med. 2013. PMID: 24050937 Free article.

2

Effect of cyclosporin A administration on the biodistribution and multipinhole muSPECT imaging of [123I]R91150 in rodent brain.

Blanckaert P, Burvenich I, Staelens S, De Bruyne S, Moerman L, Wyffels L, De Vos F. Blanckaert P, et al. Among authors: wyffels l. Eur J Nucl Med Mol Imaging. 2009 Mar;36(3):446-53. doi: 10.1007/s00259-008-0968-x. Epub 2008 Nov 5. Eur J Nucl Med Mol Imaging. 2009. PMID: 18985346

3

In vivo evaluation in rodents of [(123)I]-3-I-CO as a potential SPECT tracer for the serotonin 5-HT(2A) receptor.

Blanckaert PB, Burvenich I, Wyffels L, De Bruyne S, Moerman L, De Vos F. Blanckaert PB, et al. Among authors: wyffels l. Nucl Med Biol. 2008 Nov;35(8):861-7. doi: 10.1016/j.nucmedbio.2008.09.004. Nucl Med Biol. 2008. PMID: 19026947

4

Radiosynthesis and in vivo evaluation of [11C]-labelled pyrrole-2-carboxamide derivates as novel radioligands for PET imaging of monoamine oxidase A.

De Bruyne S, La Regina G, Staelens S, Wyffels L, Deleye S, Silvestri R, De Vos F. De Bruyne S, et al. Among authors: wyffels l. Nucl Med Biol. 2010 May;37(4):459-67. doi: 10.1016/j.nucmedbio.2009.09.005. Epub 2010 Apr 8. Nucl Med Biol. 2010. PMID: 20447558

5

In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter.

De Bruyne S, Wyffels L, Boos TL, Staelens S, Deleye S, Rice KC, De Vos F. De Bruyne S, et al. Among authors: wyffels l. Nucl Med Biol. 2010 May;37(4):469-77. doi: 10.1016/j.nucmedbio.2009.10.006. Epub 2010 Apr 7. Nucl Med Biol. 2010. PMID: 20447559

6

PET imaging of fatty acid amide hydrolase in the brain: synthesis and biological evaluation of an 11C-labelled URB597 analogue.

Wyffels L, Muccioli GG, Kapanda CN, Labar G, De Bruyne S, De Vos F, Lambert DM. Wyffels L, et al. Nucl Med Biol. 2010 Jul;37(5):665-75. doi: 10.1016/j.nucmedbio.2010.03.009. Epub 2010 May 6. Nucl Med Biol. 2010. PMID: 20610171

7

Towards a reproducible protocol for repetitive and semi-quantitative rat brain imaging with (18) F-FDG: exemplified in a memantine pharmacological challenge.

Deleye S, Verhaeghe J, wyffels L, Dedeurwaerdere S, Stroobants S, Staelens S. Deleye S, et al. Among authors: wyffels l. Neuroimage. 2014 Aug 1;96:276-87. doi: 10.1016/j.neuroimage.2014.04.004. Epub 2014 Apr 13. Neuroimage. 2014. PMID: 24736171

8

Synthesis and in vivo preclinical evaluation of an (18)F labeled uPA inhibitor as a potential PET imaging agent.

Ides J, Thomae D, Wyffels L, Vangestel C, Messagie J, Joossens J, Lardon F, Van der Veken P, Augustyns K, Stroobants S, Staelens S. Ides J, et al. Among authors: wyffels l. Nucl Med Biol. 2014 Jul;41(6):477-87. doi: 10.1016/j.nucmedbio.2014.03.019. Epub 2014 Mar 29. Nucl Med Biol. 2014. PMID: 24768145

9

In vivo evaluation of (18)F-labeled TCO for pre-targeted PET imaging in the brain.

Wyffels L, Thomae D, Waldron AM, Fissers J, Dedeurwaerdere S, Van der Veken P, Joossens J, Stroobants S, Augustyns K, Staelens S. Wyffels L, et al. Nucl Med Biol. 2014 Jul;41(6):513-23. doi: 10.1016/j.nucmedbio.2014.03.023. Epub 2014 Apr 2. Nucl Med Biol. 2014. PMID: 24768149

10

The [18F]FDG μPET readout of a brain activation model to evaluate the metabotropic glutamate receptor 2 positive allosteric modulator JNJ-42153605.

Wyckhuys T, Wyffels L, Langlois X, Schmidt M, Stroobants S, Staelens S. Wyckhuys T, et al. Among authors: wyffels l. J Pharmacol Exp Ther. 2014 Aug;350(2):375-86. doi: 10.1124/jpet.114.213959. Epub 2014 Jun 4. J Pharmacol Exp Ther. 2014. PMID: 24898267

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