Shuto S - Search Results

1

Conformational restriction approach to β-secretase (BACE1) inhibitors III: effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations.

Yonezawa S, Fujiwara K, Yamamoto T, Hattori K, Yamakawa H, Muto C, Hosono M, Tanaka Y, Nakano T, Takemoto H, Arisawa M, Shuto S. Yonezawa S, et al. Among authors: shuto s. Bioorg Med Chem. 2013 Nov 1;21(21):6506-22. doi: 10.1016/j.bmc.2013.08.036. Epub 2013 Aug 28. Bioorg Med Chem. 2013. PMID: 24051074

2

Nucleosides and nucleotides--CXXXVII. Antitumor phospholipids with 5-fluorouridine as a cytotoxic polar-head: synthesis of 5'-phosphatidyl-5-fluorouridines by phospholipase D-catalyzed transphosphatidylation.

Shuto S, Itoh H, Sakai A, Nakagami K, Imamura S, Matsuda A. Shuto S, et al. Bioorg Med Chem. 1995 Mar;3(3):235-43. doi: 10.1016/0968-0896(95)00003-y. Bioorg Med Chem. 1995. PMID: 7606385

3

(+/-)-(Z)-2-(aminomethyl)-1-phenylcyclopropanecarboxamide derivatives as a new prototype of NMDA receptor antagonists.

Shuto S, Takada H, Mochizuki D, Tsujita R, Hase Y, Ono S, Shibuya N, Matsuda A. Shuto S, et al. J Med Chem. 1995 Jul 21;38(15):2964-8. doi: 10.1021/jm00015a019. J Med Chem. 1995. PMID: 7636857

4

New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1.

Shuto S, Obara T, Saito Y, Andrei G, Snoeck R, De Clercq E, Matsuda A. Shuto S, et al. J Med Chem. 1996 Jun 7;39(12):2392-9. doi: 10.1021/jm950853f. J Med Chem. 1996. PMID: 8691433

5

Synthesis and biological activity of conformationally restricted analogs of milnacipran: (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxami de, an efficient noncompetitive N-methyl-D-aspartic acid receptor antagonist.

Shuto S, Ono S, Hase Y, Ueno Y, Noguchi T, Yoshii K, Matsuda A. Shuto S, et al. J Med Chem. 1996 Nov 22;39(24):4844-52. doi: 10.1021/jm960495w. J Med Chem. 1996. PMID: 8941398

6

Nucleosides and nucleotides. 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and -uracil1.

Hattori H, Nozawa E, Iino T, Yoshimura Y, Shuto S, Shimamoto Y, Nomura M, Fukushima M, Tanaka M, Sasaki T, Matsuda A. Hattori H, et al. Among authors: shuto s. J Med Chem. 1998 Jul 16;41(15):2892-902. doi: 10.1021/jm9801814. J Med Chem. 1998. PMID: 9667977

7

Synthesis and biological activity of conformationally restricted analogues of milnacipran: (1S, 2R)-1-phenyl-2-[(R)-1-amino-2-propynyl]-N,N- diethylcyclopropanecarboxamide is a novel class of NMDA receptor channel blocker.

Shuto S, Ono S, Imoto H, Yoshii K, Matsuda A. Shuto S, et al. J Med Chem. 1998 Aug 27;41(18):3507-14. doi: 10.1021/jm980238m. J Med Chem. 1998. PMID: 9719604

8

Nucleosides and nucleotides. 183. Synthesis of 4'alpha-branched thymidines as a new type of antiviral agent.

Sugimoto I, Shuto S, Mori S, Shigeta S, Matsuda A. Sugimoto I, et al. Among authors: shuto s. Bioorg Med Chem Lett. 1999 Feb 8;9(3):385-8. doi: 10.1016/s0960-894x(99)00010-4. Bioorg Med Chem Lett. 1999. PMID: 10091689

9

Nucleosides and nucleotides. 185. Synthesis and biological activities of 4'alpha-C-branched-chain sugar pyrimidine nucleosides.

Nomura M, Shuto S, Tanaka M, Sasaki T, Mori S, Shigeta S, Matsuda A. Nomura M, et al. Among authors: shuto s. J Med Chem. 1999 Jul 29;42(15):2901-8. doi: 10.1021/jm990050i. J Med Chem. 1999. PMID: 10425099

10

Total synthesis of cyclic ADP-carbocyclic-ribose, a stable mimic of Ca2+-mobilizing second messenger cyclic ADP-ribose.

Shuto S, Fukuoka M, Manikowsky A, Ueno Y, Nakano T, Kuroda R, Kuroda H, Matsuda A. Shuto S, et al. J Am Chem Soc. 2001 Sep 12;123(36):8750-9. doi: 10.1021/ja010756d. J Am Chem Soc. 2001. PMID: 11535079

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